So many variable causes influence mortality that the tables which represent it ought to be changed according to place and time. The divers states of life offer in this regard appreciable differences relative to the fatigues and the dangers inseparable from each state and of which it is indispensable to keep account in the calculations founded upon the duration of life. But these differences have not been sufficiently observed. Some day they will be and then will be known what sacrifice of life each profession demands and one will profit by this knowledge to diminish the dangers.

The greater or less salubrity of the soil, its elevation, its temperature, the customs of the inhabitants, and the operations of governments have a considerable influence upon mortality. But it is always necessary to precede the investigation of the cause of the differences observed by that of the probability with which this cause is indicated. Thus the ratio of the population to annual births, which one has seen raised in France to twenty-eight and one third, is not equal to twenty-five in the ancient duchy of Milan. These ratios, both established upon a great number of births, do not permit of calling into question the existence among the Milanese of a special cause of mortality, which it is of moment for the government of our country to investigate and remove.

The ratio of the population to the births would increase again if we could diminish and remove certain dangerous and widely spread maladies. This has happily been done for the smallpox, at first by the inoculation of this disease, then in a manner much more advantageous, by the inoculation of vaccine, the inestimable discovery of Jenner, who has thereby become one of the greatest benefactors of humanity.

The smallpox has this in particular, namely, that the same individual is not twice affected by it, or at least such cases are so rare that they may be abstracted from the calculation. This malady, from which few escaped before the discovery of vaccine, is often fatal and causes the death of one seventh of those whom it attacks. Sometimes it is mild, and experience has taught that it can be given this latter character by inoculating it upon healthy persons, prepared for it by a proper diet and in a favorable season. Then the ratio of the individuals who die to the inoculated ones is not one three hundredth. This great advantage of inoculation, joined to those of not altering the appearance and of preserving from the grievous consequences which the natural smallpox often brings, caused it to be adopted by a great number of persons. The practice was strongly recommended, but it was strongly combated, as is nearly always the case in things subject to inconvenience. In the midst of this dispute Daniel Bernoulli proposed to submit to the calculus of probabilities the influence of inoculation upon the mean duration of life. Since precise data of the mortality produced by the smallpox at the various ages of life were lacking, he supposed that the danger of having this malady and that of dying of it are the same at every age. By means of these suppositions he succeeded by a delicate analysis in converting an ordinary table of mortality into that which would be used if smallpox did not exist, or if it caused the death of only a very small number of those affected, and he concludes from it that inoculation would augment by three years at least the mean duration of life, which appeared to him beyond doubt the advantage of this operation. D'Alembert attacked the analysis of Bernoulli: at first in regard to the uncertainty of his two hypotheses, then in regard to its insufficiency in this, that no comparison was made of the immediate danger, although very small, of dying of inoculation, to the very great but very remote danger of succumbing to natural smallpox. This consideration, which disappears when one considers a great number of individuals, is for this reason immaterial for governments and the advantages of inoculation for them still remain; but it is of great weight for the father of a family who must fear, in having his children inoculated, to see that one perish whom he holds most dear and to be the cause of it. Many parents were restrained by this fear, which the discovery of vaccine has happily dissipated. By one of those mysteries which nature offers to us so frequently, vaccine is a preventive of smallpox just as certain as variolar virus, and there is no danger at all; it does not expose to any malady and demands only very little care. Therefore the practice of it has spread quickly; and to render it universal it remains only to overcome the natural inertia of the people, against which it is necessary to strive continually, even when it is a question of their dearest interests.

The simplest means of calculating the advantage which the extinction of a malady would produce consists in determining by observation the number of individuals of a given age who die of it each year and subtracting this number from the number of deaths at the same age. The ratio of the difference to the total number of individuals of the given age would be the probability of dying in the year at this age if the malady did not exist. Making, then, a sum of these probabilities from birth up to any given age, and subtracting this sum from unity, the remainder will be the probability of living to that age corresponding to the extinction of the malady. The series of these probabilities will be the table of mortality relative to this hypothesis, and we may conclude from it, by what precedes, the mean duration of life. It is thus that Duvilard has found that the increase of the mean duration of life, due to inoculation with vaccine, is three years at the least. An increase so considerable would produce a very great increase in the population if the latter, for other reasons, were not restrained by the relative diminution of subsistences.

It is principally by the lack of subsistences that the progressive march of the population is arrested. In all kinds of animals and vegetables, nature tends without ceasing to augment the number of individuals until they are on a level of the means of subsistence. In the human race moral causes have a great influence upon the population. If easy clearings of the forest can furnish an abundant nourishment for new generations, the certainty of being able to support a numerous family encourages marriages and renders them more productive. Upon the same soil the population and the births ought to increase at the same time simultaneously in geometric progression. But when clearings become more difficult and more rare then the increase of population diminishes; it approaches continually the variable state of subsistences, making oscillations about it just as a pendulum whose periodicity is retarded by changing the point of suspension, oscillates about this point by virtue of its own weight. It is difficult to evaluate the maximum increase of the population; it appears after observations that in favorable circumstances the population of the human race would be doubled every fifteen years. We estimate that in North America the period of this doubling is twenty-two years. In this state of things, the population, births, marriages, mortality, all increase according to the same geometric progression of which we have the constant ratio of consecutive terms by the observation of annual births at two epochs.

By means of a table of mortality representing the probabilities of human life, we may determine the duration of marriages. Supposing in order to simplify the matter that the mortality is the same for the two sexes, we shall obtain the probability that the marriage will subsist one year, or two, or three, etc., by forming a series of fractions whose common denominator is the product of the two numbers of the table corresponding to the ages of the consorts, and whose numerators are the successive products of the numbers corresponding to these ages augmented by one, by two, by three, etc., years. The sum of these fractions augmented by one half will be the mean duration of marriage, the year being taken as unity. It is easy to extend the same rule to the mean duration of an association formed of three or of a greater number of individuals.

CHAPTER XV.
CONCERNING THE BENEFITS OF INSTITUTIONS WHICH DEPEND UPON THE PROBABILITY OF EVENTS.

Let us recall here what has been said in speaking of hope. It has been seen that in order to obtain the advantage which results from several simple events, of which the ones produce a benefit and the others a loss, it is necessary to add the products of the probability of each favorable event by the benefit which it procures, and subtract from their sum that of the products of the probability of each unfavorable event by the loss which is attached to it. But whatever may be the advantage expressed by the difference of these sums, a single event composed of these simple events does not guarantee against the fear of experiencing a loss. One imagines that this fear ought to decrease when one multiplies the compound event. The analysis of probabilities leads to this general theorem.