Following up their supremacy on the sea, the Knights continued to fight the Turks and Greeks, wherever found, until at last scarcely a vessel bearing the flag of either of them dared to venture out of port. Four times the Mussulmans made prodigious efforts to dislodge the Knights from Rhodes; but on each occasion they were signally defeated. The warlike Turks grew more and more formidable, while they were constantly goaded by the fresh aggressions of the Knights.

Besides being actuated by a desire for revenge upon an enemy who had not only so nearly ruined the commerce of Turkey, but who had raided so many of the unprotected coast towns, carrying off the inhabitants and selling them into slavery, Solyman, Sultan of Turkey, was burning with envy. He coveted the island, which, under the Knights of St. John, had been made to "blossom like the rose." So he "swore by his own head," says an ancient writer, that he would possess Rhodes, if it cost the lives of half his army to conquer it. Vast preparations were therefore made to carry on, if necessary, a protracted siege. At great labor and expense all the available forces of the Ottoman navy and army were brought together and organized for this purpose, in the year 1522. The writers of that period tell us that two hundred thousand men were transported to Rhodes from Constantinople, commanded by the emperor in person. To oppose this gigantic host the order could bring but six or seven hundred Knights and less than six thousand men-at-arms. But every Knight was a host in himself, while the common soldiers were well armed and thoroughly disciplined.

The army of the Sultan took position before the fortifications of Rhodes with all their implements of war, in a manner which showed that they had come to stay until victory should perch upon their banners. They stormed the stout defenses again and again, with great loss of life on their part. The Knights gallantly withstood all their furious and frenzied efforts for a period of six months, often sallying forth and slaughtering myriads of the Ottomans in hand-to-hand conflicts. The Turks did not lack for courage. They always fought with desperation; but in personal conflict, man to man, they were no match for the stout cavaliers of the white cross, who, besides having the advantage of weight and physical strength, were protected by impenetrable steel armor, while the Orientals wore only their flowing robes and turbans of linen. Vastly outnumbering the Knights, this very disproportion was to their disadvantage, often causing them to be swept out of existence by the score, from the solid phalanx which they presented to the keen weapons of the Christians. The light arms and the agility of the soldiers of the Sultan were of little comparative avail when met by the heavy blows and ponderous battle-axes wielded by stout Europeans. Among the vows of the Knights was a most significant one, namely, "never to reckon the number of an enemy." Vast superiority of numbers, however, told at last, for the besieged were utterly worn out. Quarter was neither asked nor given by either side; but when the combatants met, they fought to the last gasp. It was a war of extermination on the part of both Christians and Turks. The latter, being really the weaker party, went down by hundreds.

Including the killed and severely wounded, together with those who died of fever and various diseases incident to camp life, it is authoritatively stated that the Turks lost one hundred and sixty thousand men in the six months' siege of Rhodes, showing a dogged persistency which was probably never surpassed, if it has been equaled, in warfare. It should be remembered that the enormous host of the Ottomans was opposed by only about five or six thousand men, who, however, mostly fought from behind protecting stone walls.

In order to show the spirit which actuated the Knights, and their unscrupulous mode of warfare, we will relate a well-authenticated instance connected with this remarkable siege.

One of the famous fighters in the ranks of the Order of St. John was a Frenchman who bore the name of Fornonius, who is declared to have killed over six hundred of the enemy during the six months' contest! His prowess was not only marvelous in the open field and upon the ramparts when engaged in repelling an assault, but he would lie in wait, like a hunter of wild beasts, for hours together, to obtain the chance of killing a Mussulman. When a sortie was made against the besiegers, Fornonius was always found in the van, rushing among the enemy, and with one terrible sweeping reach of his keen-edged battle-axe, he would sever three or four heads from their bodies, keeping up a shower of these frightful blows, aimed right and left, until the astonished Ottomans, notwithstanding their usually reckless bravery, fled in utter dismay before what seemed to them a superhuman power. Even his comrades believed that he bore a charmed life; for, although he received many slight wounds, he was never touched in a vital part, and he boasted that he had not been out of "fighting trim" during the whole of that long siege, night or day. His example was in a degree contagious, and the Knights, thoroughly trained to the use of arms, vied with each other in their murderous efforts against the common enemy.

This gallant, though in one sense useless defense of the island was sustained so long and so successfully against such desperate odds, as to establish the fame of the Knights for persistent bravery, commanding even the respect and admiration of their enemies. The Turks had resolved upon the conquest of the place, let it cost what blood it might, and were constantly reinforced by fresh troops from Constantinople. Although the Knights were finally obliged to yield, they were enabled to retire from Rhodes upon advantageous terms, or to use the military phrase, upon "honorable" terms. It was on this historic occasion that Charles V. exclaimed in admiration: "There has been nothing so well lost in the world as Rhodes."

The Sultan of Turkey, to the great surprise of all the world, which had been looking on with deepest interest at this sanguinary struggle upon the most beautiful island of the Levant, proved himself to be, as an enemy, brave and persistent; as a conqueror, mild and merciful. The Knights, during the long period in which they had possessed Rhodes, had not failed to attack every galley bearing the Ottoman flag which they sighted, nor hesitated to destroy every coast town belonging to that power which they could reach, or to burn any Mohammedan mosque when they got near enough to apply the torch. Added to all this, they had constantly captured and carried into slavery Turkish men, women, and children by the hundreds. The Sultan, under such aggravating circumstances, would have been fully justified, according to the code of warfare practiced in those days, in putting every belligerent whom he found in Rhodes to the sword. To conquer the island had cost him a vast amount of treasure, together with a hundred and sixty thousand of his best soldiers,—a terrible price to pay for victory. Notwithstanding this long list of bitter aggressions, according to our idea, Sultan Solyman showed himself to be far more humane and generous than did the professed Christians of the Order of St. John.

The liberal and remarkable terms granted by the conquerors of Rhodes were in brief as follows:—

The Knights agreed to promptly and peaceably evacuate the island and its dependencies within twelve days, being permitted to take with them their arms and personal effects, even including such church ornaments and treasures as they chose to move. Those of the citizens of Rhodes who desired to do so could depart in the same manner, while the Christians who remained were to be unmolested, and permitted to worship in their usual manner. The Sultan was to provide ships, and to provision them, with which to transport to Crete all who desired to go thither. These liberal, not to say generous terms were faithfully adhered to, except in one instance,—all the Christian churches in Rhodes were promptly turned into Mohammedan mosques.