To cross the curious workmanship of nature,

To mingle beauty with infirmities,

And pure perfection with impure defeature;

Making it subject to the tyranny

Of sad mischances and much misery;

As burning fevers, agues pale and faint,

Life-poisoning pestilence, and frenzies wood,

The marrow-eating sickness, whose attaint

Disorder breeds by heating of the blood:

Surfeits, impostumes, grief, and damn'd despair—