CHART TO EXPT. No. I. (cp. Table, page 89. The figures in the chart refer to comparative surfaces.)
Thick line—total number of leucocytes
Broken line—lymphocytes
Thin line—number of nucleated, pseudo-eosinophil cells
Double line—large mononuclear cells
Dotted line—eosinophil cells
TABLE I.
Key to columns:
A -
B - Pseudo-eosinophil cells
C - Lymphocytes
D - Large mononuclear cells
E - Eosinophil cells
F - Nigrosinopil cells
G - On comparative surfaces
| Date | Leucocytes | Pseudo-eosinophil cells | Lymphocytes | Large mononuclear cells | Eosinophil cells | Nigrosinopil cells | ||||||||||||
| Total | On comparative surfaces | % | On comparative surfaces | % | On comparative surfaces | % | On comparative surfaces | % | On comparative surfaces | % | On comparative surfaces | |||||||
| 1888 | ||||||||||||||||||
| April 19 | 500 | — | 44.7 | — | 35.4 | — | 18.4 | — | 1.1 | — | 0.5 | — | ||||||
| 23 | 990 | 24 | 40.4 | 9.7 | 35.6 | 8.5 | 21.6 | 5.2 | 1.9 | 0.4 | 0.4 | 0.09 | ||||||
| May 1 | 858 | 28 | 47.0 | 13.6 | 32.6 | 9.1 | 18.0 | 5.0 | 0.9 | 0.2 | 0.3 | 0.08 | ||||||
| 8 | 934 | 28 | 45.2 | 12.6 | 40.3 | 11.3 | 14.3 | 4.0 | 0.6 | 0.2 | 0.4 | 0.1 | ||||||
| 16 | 1122 | 30 | 38.4 | 11.5 | 47.7 | 14.3 | 10.3 | 3.1 | 3.3 | 0.9 | 0.2 | 0.06 | ||||||
| 24 | 1722 | 35 | 40.1 | 14.0 | 35.0 | 12.2 | 23.6 | 8.3 | 1.0 | 0.3 | 0.1 | 0.03 | ||||||
| 30 | 900 | 30 | 36.6 | 10.9 | 44.4 | 13.3 | 18.4 | 5.5 | 0.1 | 0.03 | 0.3 | 0.09 | ||||||
| June 5 | 825 | 33 | 28.4 | 9.4 | 49.3 | 16.2 | 20.0 | 6.6 | 1.7 | 0.6 | 0.4 | 0.1 | ||||||
| 12 | 1314 | 33 | 28.0 | 9.3 | 49.0 | 16.2 | 20.0 | 6.6 | 2.2 | 0.7 | 0.8 | 0.3 | ||||||
| 19 | 917 | 37 | 32.4 | 11.9 | 52.3 | 19.3 | 14.5 | 5.4 | 0.6 | 0.3 | 0.2 | 0.07 | ||||||
| 28 | 802 | 42 | 30.5 | 12.8 | 56.4 | 23.7 | 11.7 | 4.9 | 0.7 | 0.3 | 0.4 | 0.2 | ||||||
| July 2 | 1062 | 56 | 16.5 | 9.2 | 57.1 | 31.9 | 25.6 | 10.3 | 1.2 | 0.7 | 1.2 | 0.7 | ||||||
| 9 | 1245 | 51 | 17.6 | 8.9 | 59.1 | 30.1 | 21.8 | 11.1 | 0.8 | 0.4 | 0.8 | 0.4 | ||||||
| 16 | 974 | 69 | 17.5 | 12.0 | 66.4 | 45.8 | 15.7 | 10.8 | 0.2 | 0.1 | 0.2 | 0.1 | ||||||
| 23 | 1156 | 58 | 21.7 | 12.6 | 67.2 | 38.9 | 9.5 | 5.5 | 1.5 | 0.9 | 0.2 | 0.1 | ||||||
| 30 | 802 | 54 | 20.2 | 10.7 | 65.4 | 34.6 | 12.8 | 6.8 | 1.4 | 0.7 | — | — | ||||||
| Aug. 6 | 910 | 52 | 21.7 | 11.3 | 67.3 | 34.9 | 9.7 | 4.9 | 1.0 | 0.5 | 0.3 | 0.2 | ||||||
| Sept. 6 | 815 | 51 | 23.0 | 11.7 | 65.3 | 33.5 | 9.8 | 4.9 | 0.9 | 0.5 | 0.4 | 0.2 | ||||||
| Oct. 5 | 625 | 62 | 26.4 | 16.3 | 64.4 | 39.9 | 8.5 | 5.2 | 0.6 | 0.4 | — | — | ||||||
| Nov. 4 | 800 | 58 | 22.5 | 13.0 | 66.4 | 38.5 | 9.6 | 7.3 | 0.9 | 0.5 | 0.5 | 0.2 | ||||||
| 1889 | ||||||||||||||||||
| April 10 | 700 | — | 29.8 | — | 53.3 | — | 14.8 | — | 1.2 | — | 0.6 | — | ||||||
| June 6 | 900 | 71 | 28.2 | 20.0 | 50.1 | 35.6 | 12.9 | 9.1 | 8.2 | 5.8 | 0.6 | 0.4 | ||||||
| Aug. 1 | 670 | 62 | 30.6 | 18.9 | 44.2 | 27.4 | 15.2 | 9.4 | 9.6 | 5.9 | 0.4 | 0.2 | ||||||
| Dec. 4 | 731 | 63 | 36.0 | 22.0 | 38.3 | 24.1 | 11.3 | 7.1 | 13.3 | 8.7 | 0.6 | 0.4 | ||||||
| 1890 | ||||||||||||||||||
| Feb. 2 | 622 | 51 | 32.3 | 16.5 | 30.1 | 15.3 | 11.1 | 5.6 | 26.0 | 13.2 | 0.5 | 0.2 | ||||||
| April 30 | 500 | 48 | 36.5 | 17.5 | 24.5 | 11.7 | 9.4 | 4.5 | 28.9 | 13.9 | 0.6 | 0.3 | ||||||
The results of further investigations, which we here shortly repeat in tabular form, shew that in this experiment No. I. we are not dealing with an abnormal phenomenon of an exceptional animal.
| No. of Expt. | Number of white blood corpuscles | ||
| Before the splenectomy | At the end of the first year | At the end of the second year | |
| 1 | 10,700 | 14,200 | 18,000 |
| 2 | 12,000 | 27,600 | 32,000 |
| 4 | 15,000 | 19,200 | 19,000 |
| Average | 12,600 | 20,333 | 23,300 |
By estimating the percentage proportion of the single kinds of white corpuscles, Kurloff obtained the following result:
| Before the operation | At the end of the first year | At the end of the second year | ||||||||||||
| Number of the Exper- iment | Polynuclear granular cells | Lympho- cytes | Mono- nuclear | Eosin- ophil | Polynuclear granular cells | Lympho- cytes | Mono- nuclear | Eosin- ophil | Polynuclear granular cells | Lympho- cytes | Mono- nuclear | Eosin- ophil | ||
| 1 | 4782 | 3788 | 1969 | 117 | 4232 | 1568 | 2101 | 170 | 6570 | 4410 | 1692 | 5202 | ||
| 2 | 6276 | 3360 | 2244 | 72 | 5464 | 16615 | 2980 | 2539 | 5824 | 20861 | 2688 | 2240 | ||
| 4 | 6715 | 5250 | 2595 | 450 | 6568 | 10041 | 3686 | 96 | 7108 | 3009 | 2138 | 7543 | ||
From these researches we draw the following conclusions.