G. SIMS WOODHEAD.
NOTE BY THE TRANSLATOR.
This translation of the first part of Die Anæmie, Nothnagel's Specielle Pathologie und Therapie, vol. viii. was carried out under the personal guidance of Professor Ehrlich. Several alterations and additions have been made in the present edition. To my friend Dr Cobbett I owe a debt of gratitude for his kind help in the revision of the proof-sheets.
W. M.
CONTENTS.
PAGE
INTRODUCTION [1]
Definition. Clinical methods of investigation of the blood [1]
The quantity of the blood [2]
Number of red corpuscles [4]
Size of red corpuscles [12]
Amount of hæmoglobin in the blood [13]
Specific gravity of the blood [17]
Hygrometry [21]
Total volume of the red corpuscles [21]
Alkalinity of the blood [23]
Coagulability of the blood [24]
Separation of the serum [24]
Resistance of the red corpuscles [25]
THE MORPHOLOGY OF THE BLOOD [27]
A. Methods of investigation [29]
α. Preparation of the dry specimen [32]
β. Fixation of the dry specimen [34]
γ. Staining of the dry specimen [36]
Theory of staining [37]
Combined staining [38]
Triacid fluid [40]
Other staining fluids [41]
Recognition of glycogen in the blood [45]
Microscopic determination of the distribution of the alkali of the blood [46]
B. Normal and pathological histology of the blood [48]
The red blood corpuscles [48]
Diminution of hæmoglobin equivalent [49]
Anæmic or polychromatophil degeneration [49]
Poikilocytosis [52]
Nucleated red blood corpuscles [54]
Normoblasts and megaloblasts [56]
The fate of the nuclei of the erythroblasts [57]
The clinical differences in the erythroblasts [61]
THE WHITE BLOOD CORPUSCLES [67]
I. Normal histology and classification of the white blood corpuscles [71]
The lymphocytes [71]
The large mononuclear leucocytes [73]
The transitional forms [74]
The polynuclear leucocytes [75]
The eosinophil cells [76]
The mast cells [76]
Pathological forms of white blood corpuscles [77]
The neutrophil myelocytes [77]
The eosinophil myelocytes [78]
The neutrophil pseudolymphocytes [78]
Stimulation forms [79]
II. On the places of origin of the white blood
corpuscles [81]
α. The spleen [84]
β. The lymphatic glands [100]
γ. The bone-marrow [105]
III. On the demonstration of the cell-granules,
and their significance [121]
History of the investigation of the granules [121]
Since Ehrlich. [123]
Methods of demonstration [124]
Vital staining of granules [124]
The Bioblast theory (Altmann) [128]
The granules as metabolic products of the cells (Ehrlich) [130]
Secretory processes in granulated cells [134]
IV. Leucocytosis [138]
Biological importance of leucocytosis [138]
Morphology of leucocytosis [142]
α. 1. Polynuclear neutrophil leucocytosis [143]
Definition [143]
Clinical occurrence [144]
Origin [144]
α. 2. Polynuclear eosinophil leucocytosis, including
the mast cells [148]
Definition [149]
Clinical occurrence [150]
Origin [154]
β. Leukæmia ("mixed leucocytosis") [167]
Lymphatic leukæmia [170]
Myelogenous leukæmia [171]
Morphological character [187]
Origin [187]
V. Leukopenia [188]
The blood platelets. The hæmoconiæ [190]
Index To Literature [195]
Index [209]
Plates