Henry of Beaufort (1405-1447), who followed Wykeham in the bishopric, was the second son of John of Gaunt, by Catharine Swynford, and uncle of Henry V. In 1398, at the early age of twenty-one, he was made bishop of Lincoln, and in 1404 was translated to Winchester. During the reign of Henry V. he thrice filled the office of chancellor. In 1417, when ostensibly on pilgrimage to the Holy Land, he was present at the Council of Constance which was then considering the affairs of the church. At this time he was offered the cardinal's hat by Martin V. and appointed papal legate, but the bestowal of this dignity on him was resented by the English monarch, who commanded him to surrender his office at Winchester, which he declared was forfeited by his becoming a cardinal. The dispute, however, was arranged, and "the haughty cardinal, more like a soldier than a man of the church," formally received his hat at Calais in 1426. In the following year he led a crusade against the followers of Huss in Bohemia, where, during the retreat of the great army from Mies, he alone at the head of a band of English crusaders endeavoured, but in vain, to arrest the utter rout. The death of Henry V. brought about a fierce rivalry between the two great uncles, Humphrey Duke of Gloucester and the cardinal bishop of Winchester, lasting until the death of the former, which only occurred six weeks before that of Beaufort himself. During the half-century of his rule at Winchester he rebuilt St Cross and founded the "Almshouse of Noble Poverty." Shakespeare has made Beaufort a prominent figure in Parts I. and II. of "Henry VI.," but, for dramatic reasons, perhaps, he is painted very much blacker than he deserved. That he was a militant ecclesiastic, scheming and unscrupulous, is no doubt true; but he was a statesman and possessed firmness of purpose, fertility of resource, and confidence in those whom he selected to carry out his designs. His wealth was very great, for he was able to lend his nephew the king £20,000, besides spending an enormous amount in charities, including £400,000 devoted to the inmates of London prisons.

William of Waynfleete (1447-1486), a student in Wykeham's colleges at Winchester and Oxford, was first master of Winchester College, then made provost of Eton in 1443, and in 1447 succeeded Beaufort in the bishopric of Winchester. From 1449 to 1459, like his predecessor, he held the chancellor's seal, and during the Wars of the Roses was a firm adherent of Henry VI. His death took place in 1486. He founded Magdalen College, Oxford, and possibly influenced Henry in his endowment of King's College, Cambridge, and Eton. Waynfleete appears to have been a man of great piety and learning, and, as Milman observes, his actions, in advancing non-monastic institutions, reveal a sagacious fore-knowledge of the coming changes in the temporal power of the church, and were planned to maintain its supremacy in ways better adapted to the new spirit which soon after his death caused the downfall of the religious houses. The effigy of this bishop, in his chantry in the retro-choir, has been restored.

Peter Courtenay (1486-1492) was translated from Exeter to Winchester, but at neither see has he left any mark on the history, the architectural work of his period being due chiefly to his priors.

Thomas Langton (1493-1500), translated hither from Salisbury, where he was active against the adherents of Wiclif, was chosen in 1500 to occupy the see of Canterbury, but he died of the plague before his translation, and was buried in his chantry to the south of the Lady Chapel. He seems to have been enthusiastic in the cause of education, since he is said to have himself superintended the teaching of boys in his town.

Richard Fox (1500-1528) was bishop successively of Exeter, Bath and Wells, and Durham before he was appointed to Winchester. Great confidence was reposed in him by Henry VII., who chose him as godfather of the future Henry VIII. To Fox is attributed the introduction of Wolsey to the king. Yet this appears to have failed to win him the cardinal's gratitude, for, according to Fuller: "All thought Bishop Fox to die too soon, only one excepted who conceived him to live too long, Thomas Wolsey, who gaped for his bishopric." With Hugh Oldham, bishop of Exeter, Fox was joint-founder of Corpus Christi College, Oxford, the pelican in her piety, which appears on the college arms, being borne by the bishop. His fine chantry and the reconstruction of the choir aisles bear witness to his interest in the fabric of his cathedral, and he is otherwise noted for the assistance he gave to various foundations.

Thomas Wolsey (1529-1530) at length gained the coveted see, which he held in commendam with the archbishopric of York, but only for one year.

Stephen Gardiner (1531-1555), another of the more famous prelates who have held this see, is said to have been the illegitimate son of Bishop Lionel Woodville of Salisbury, brother-in-law of Edward IV. Fuller, in one of his favourite conceits, says that Gardiner retained in his wit and quick apprehension the sharpness of the air at his birthplace of Bury St Edmunds. In 1529 he became archdeacon of Norwich, and, owing to his services to Cardinal Wolsey and Henry VIII., was appointed to Winchester. On the whole, he managed to keep on good terms with the king; but his famous six articles in support of the Real Presence sent so many to the stake that the title of "the bloody statute" has clung to them. During the reign of Edward VI. he was kept prisoner in the Tower, and in 1550 was deprived of his bishopric, which was restored to him on the accession of Mary, whom he crowned at Westminster. He performed also the marriage service of Mary and Philip of Spain, mentioned on page 13. "His malice," says Fuller, "was like what is commonly said of white powder which surely discharged the bullet yet made no report, being secret in all his acts of cruelty. This made him often chide Bonner, calling him 'ass,' though not so much for killing poor people as for not doing it more cunningly." Cruel and vengeful as he was, it is yet possible that he has been rather unjustly accused of personal delight in his victims' sufferings; but, while the persecutions under Mary continue to be the worst chapter of English church history, the "hammer of heretics," as he was called, will always continue to be execrated. On his death-bed at Westminster in 1555 he is reported to have said: "I have sinned with Peter, but I have not wept with him." It has indeed been held that in his latter days he was half a Protestant at heart, though this is difficult to establish. There is preserved a rather amusing appeal of Gardiner to the Privy Council, dating from 1547. He had intended to hold in Southwark a solemn dirge and mass in memory of Henry VIII., and writes to complain that the players who flourished in the neighbourhood say that they will also have "a solemne playe to trye who shal have most resorte, they in game, or I in earnest." During Gardiner's imprisonment by Edward VI., John Poynet, once Cranmer's chaplain, held his see. As the author of "On Politique Power" (1558), where he pleads that "it is lawful to kill a tyrant," and uses some very immoderate language, Poynet may be remembered, but as an ecclesiastic he has left only a discreditable record in his short term of office. He died in 1556 in Germany, whither he had retired on the Roman Catholic revival.

John White (1556-1559), who succeeded Gardiner, was deposed by Queen Elizabeth. He was born at Farnham, and educated at Winchester. Though personally he appears to have been pious, during his tenure of the see four burnings of religious opponents took place in the diocese.