Pasteur was temporarily troubled and discouraged. But he consulted the writings of former students of silkworm diseases, and, when he discovered vibriones in those dead worms, he did not doubt that he had under his eyes a well characterized example of the flachery disease—a disease independent and distinct from the pébrine. He wrote to Duruy, and acquainted him with the results he had obtained and the obstacles he encountered. Duruy wrote back on April 9, 1867—

“Thank you for your letter and the good news it contains.

“Not very far from you, at Avignon, a statue has been erected to the Persian who imported into France the cultivation of madder; what then will not be done for the rescuer of two of our greatest industries! Do not forget to inform me when you have mastered the one or two lame facts which still stand in the way. As a citizen, as head of the Université, and, if I may say so, as your friend, I wish I could follow your experiments day by day.

“You know that I should like to found a special college at Alais. Please watch for any useful information on that subject. We will talk about it on your return.

“I am obliged to M. Gernez for his assiduous and intelligent collaboration with you.”

This letter from the great Minister is all the more interesting that it is dated from the eve of the day when the law on the reorganization of primary teaching was promulgated.

The introduction into the curriculum of historical and geographical notions; the inauguration of 10,000 schools and 30,000 adult classes; the transformation of certain flagging classical colleges into technical training schools; a constant struggle to include the teaching of girls in Université organization; reforms and improvements in general teaching; the building of laboratories, etc., etc.—into the accomplishment of all these projects Duruy carried his bold and methodical activity. No one was more suited than he to the planning out of a complete system of national education. He and Pasteur were indeed fitted to understand each other, for each had in the same degree those three forms of patriotism: love for the land, memories for the past, and hero worship.

In May, 1867, Pasteur received at Alais the news that a grand prize medal of the 1867 exhibition was conferred upon him for his works on wines. He hastened to write to Dumas—

“My dear master, ... Nothing has surprised me more—or so agreeably,—than the news of this Exhibition prize medal, which I was far from expecting. It is a new proof of your kindness, for I feel sure that I have to thank you for originating such a favour. I shall do all I can to make myself worthy of it by my perseverance in putting all difficulties aside from the subject I am now engaged in, and in which the light is growing brighter every day. If that flachery disease had not come to complicate matters, everything would be well by now. I cannot tell you how absolutely sure I now feel of my conclusions concerning the corpuscle disease. I could say a great deal about the articles of Messrs. Béchamp, Estor and Balbiani, but I will follow your advice and answer nothing....”

Dumas had been advising Pasteur not to waste his time by answering his adversaries and contradictors. Pasteur’s system was making way; ten microscopes were set up, here and there, in the town of Alais; most seed merchants were taking up the examination of the dead moths, and the Pont-Gisquet colony had samples brought in daily for inspection. “I have already prevented many failures for next year,” he wrote to Dumas (June, 1867), “but I always beg as a favour that a little of the condemned seed may be raised, so as to confirm the exactness of my judgment.”