Among the visitors at Rome the winter that Mr. Gladstone spent in the eternal city were the widow and daughters of Sir Stephen Richard Glynne, of Hawarden Castle, Flintshire, Wales. He had already made the acquaintance of these ladies, having been a friend of Lady Glynne's eldest son at Oxford, and having visited him at Hawarden in 1835. He was thrown much into their society while at Rome, and became engaged to the elder of Lady Glynne's daughters, Catharine Glynne. It is strange to relate that some time before this when Miss Glynne met her future husband at a dinner-party, an English minister sitting next to her had thus drawn her attention to Mr. Gladstone: "Mark that young man; he will yet be Prime Minister of England." Miss Glynne and her sister were known as "the handsome Miss Glynnes."

William E. Gladstone and Catharine Glynne were married July 25, 1839, at Hawarden Castle. At the same time and place Miss Mary Glynne was married to George William, fourth Lord Lyttleton, with whom Mr. Gladstone was on the most intimate terms of friendship until his lordship's untoward and lamented death. The brother of these ladies was Sir Stephen Glynne, the then owner of Hawarden. Mrs. Gladstone was "in her issue heir" of Sir Stephen Glynne, who was ninth and last baronet of that name.

The marriage ceremony has been thus described by an eye-witness:

"For some time past the little town of Hawarden has been in a state of excitement in consequence of the anticipated nuptials of the two sisters of Sir Stephen Glynne, Bart., M.P., who have been engaged for some time past to Lord Lyttelton and to Mr. W. Ewart Gladstone. Thursday last (July 25th) was fixed upon for the ceremony to take place; but in consequence of the Chartists having attacked Lord Lyttelton's mansion in Worcestershire, it was feared that the marriage would be delayed. All anxieties on this subject were put an end to by orders being issued to make ready for the ceremony, and the Hawarden folks lost no time in making due preparations accordingly. The church was elegantly and profusely decorated with laurels, while extremely handsome garlands, composed of the finest flowers, were suspended from the venerable roof. About half-past ten a simultaneous rising of the assembled multitude and the burst of melody from the organ announced that the fair brides had arrived, and all eyes were turned towards the door to witness the bridal cortege. In a few minutes more the party arrived at the communion table and the imposing ceremony commenced. At this period the coup d'oeil was extremely interesting. The bridal party exhibited every elegance of costume; while the dresses of the multitude, lit up by the rays of a brilliant sunlight, filled up the picture. The Rev. the Hon. G. Neville performed the ceremony. At its conclusion the brides visited the rectory, whence they soon afterwards set out—Lord and Lady Lyttelton to their seat in Worcestershire, and Mr. and Mrs. Gladstone on a visit to Sir Richard Brooke, Norton Priory Mansion, in Cheshire. The bridal party having returned to the castle, the good folks of Hawarden filled up the day with rambling over Sir Stephen Glynne's delightful park, to which free access was given to all comers; and towards evening a dance on the green was got up."

It is to be remarked that by his marriage Mr. Gladstone became allied with the house of Grenville, a family of statesmen, which, directly or in its ramifications, had already supplied England with four Prime Ministers. Baron Bunsen, who made his acquaintance that year, writes that he "was delighted with the man who is some day to govern England if his book is not in the way."

Mrs. Gladstone is widely and deservedly known for her many philanthropic enterprises, but even better, perhaps, has proved herself to be a noble and devoted wife and mother. She has cheered by her sympathy her illustrious husband in his defeats as well as in his triumphs, in the many great undertakings of his political career, and been to him all the late Viscountess Beaconsfield was to Mr. Gladstone's Parliamentary rival. As a mother, she nursed and reared all her children, and ever kept them in the maternal eye, carefully watching over and tending them. One of the most interesting buildings at Hawarden is Mrs. Gladstone's orphanage, which stands close to the castle. Here desolate orphans are well cared for, and find, until they are prepared to enter on the conflict and to encounter the cares of life, a happy home.