Sheep may be drenched either in the standing position, or when thrown on the haunches and held between the knees. Care should be exercised in giving irritating drenches to sheep, especially if the drench be bulky.
A herd of hogs may be quickly and easily drenched if they are confined in a small pen, and the loop of a small rope placed around the snout, well back toward the corners of the mouth. A small metal dose syringe should be used. If the drench is bulky and the hog difficult to hold, it may be necessary to elevate the head and raise the forefeet from the ground. The drench should not be given until the hog is quiet and well under control, as there is some danger of the medicine passing into the air passages and doing harm. It may be necessary to mark the hogs that have been drenched with a daub of paint, or in some other manner in order to be able to distinguish them from the untreated animals.
The administration of drugs enclosed in a gelatin capsule, or mixing them with syrup, honey or linseed oil, and rolling the mass into the form of a cylinder is commonly practised. The capsule or ball may then be shot into the pharynx with a balling gun. A ball may also be given to the larger animals by carrying it into the back part of the mouth with the hand, and placing it on the back part of the tongue. In the horse this method of administration requires some practice. The tongue must be pulled well forward, the head held up, and the tongue released as soon as the ball is placed on the tongue, so that it may pass back into the pharynx.
The administration of drugs by injecting beneath the skin (Fig. 7) is suitable when the drug is non-irritating and the dose is small. Drugs administered in this way act promptly and energetically. The alkaloid or active principle of the drug is commonly used. A fold of the skin is picked up with the fingers and the needle is quickly introduced, care being taken not to prick or scratch the muscular tissue, as this causes some pain and makes the animal restless. In order to avoid abscess formation at the point of injection, the skin should be cleansed with a disinfectant and the syringe and needle sterilized before using.
[Illustration: FIG. 7.—Hypodermic syringes.]
Drugs are not absorbed through the unbroken skin, but when applied with friction, or when the outer layer is removed by blistering, absorption may take place. Liniments, blisters and poultices are the preparations used.
Volatile drugs, such as chloroform and ether, are absorbed quickly by the enormous vascular surface of the lungs. This class of drugs is administered for the purpose of producing general anaesthesia. Anaesthetics are indispensable in many surgical operations.
The administration of a drug in the form of medicated steam is quite useful in combating some respiratory diseases. In steaming large animals a pail about half full of boiling-hot water to which has been added about an ounce of coal-tar disinfectant, or whatever drug is required, is held within about one foot of the animal's nostrils. It is usually advisable to throw a light cover over the head and pail in order to direct the steam toward the nostrils. Dogs can be placed on a cane-seated chair and a pail or pan of boiling-hot water placed under it, and a sheet thrown over all.
Drugs are administered by way of the rectum when the animal can not be drenched, or the drug can not be given in any other way and when a local action is desired. An enema or clyster is a fluid injection into the rectum and is employed for the following purposes: to accelerate the action of a purgative; to stimulate the peristaltic movement of the intestines; to kill intestinal parasites; to reduce body temperature; to administer medicine; and to supply the animal with food. An enema may be administered by allowing water to gravitate into the rectum from a height of two or three feet or by using an injection pump. In the larger animals several feet of heavy walled rubber tubing carrying a straight nozzle at one end should be used. In administering an enema, the rectum should be emptied out with the hand and the nozzle of the syringe carried as far forward as possible. The operator should be careful not to irritate or tear the wall of the rectum.
Size of the Dose.—The doses recommended in the treatment of the different diseases, unless otherwise stated, are for mature animals. The dose for a colt one year of age is about one-third the quantity given the adult, two years of age one-half, and three years of age two-thirds. In well-matured colts a larger dose may be given. In cattle, the doses recommended are about the same. In the smaller animals the size of the dose may be based on the development and age of the animal. When the drug is administered at short intervals or repeated, the size of the dose should be reduced. The physiological action of some drugs may be changed by varying the size of the dose.