The disease-producing germs are present in the body of the foetus, the fetal membranes, the discharge from the maternal passages, the faeces and milk of aborting animals. The male may carry the infection in the sheath, urethra and on the penis. The natural avenues of infection are the maternal passages and digestive tract.

It is very seldom that abortion is carried from one herd to another by means other than through the breeding of animals free from abortion to animals affected by this disease. The purchase of a bull or cow from an infected herd and breeding them to animals that are free from disease, is a common method of spreading the disease. After serving the diseased animal, the male may carry the bacillus of abortion into the maternal passages of the next cow he serves. There are numerous cases on record where the bull was a permanent carrier of the Bacillus abortus and infected nearly every animal served. The distribution of the disease in the herd following the introduction of a cow, sow, or ewe that has aborted before or after being purchased, takes place through contact of the other animals with the virus that may be present on the floor, or in the manure, or by taking the virus into the digestive tract along with the feed and drinking water. Experimental evidence indicates the latter avenue of infection.

The stallion is the most common source of infectious abortion in mares. An infected stallion may distribute the disease to a large percentage of the mares that he serves. For this reason nearly all of the mares in a certain locality may abort.

In case the infection occurs at the time of service, the abortion usually takes place during the first half of the period of pregnancy. Cows that become pregnant without recovering from the inflammation of the lining membrane of the genital tract, may abort at a very early period. McFadyean and Stockman from the artificially inoculated cases of infectious abortion in cows, showed that the period of incubation averaged 126 days.

The symptoms of accidental abortion are extremely variable. Animals that abort during the early periods of pregnancy may show so little disturbance, that the animal can be treated as if nothing had happened. During the latter half of pregnancy, and especially when the accident is caused by an injury, the symptoms are more serious. Loss of appetite, dulness, restlessness, abdominal pain and haemorrhage are the symptoms commonly noted. If the foetus is dead, it may be necessary to assist the animal in expelling it. In the latter case, death of the mother may occur.

A slight falling of the flanks, swelling of the lips of the vulva and a retention of the fetal membranes, or discharge from the vulva may be the only symptoms noted at the time abortion occurs.

The symptoms of infectious abortion vary in the different periods of pregnancy. At an early period, the foetus may be passed with so little evidence of labor that the animal pays little attention to it. The recurrence of heat may be the first intimation of the abortion. All cases of abortion are followed by more or less discharge from the vulva. This is especially true if the fetal membranes are retained. In such cases, the discharge has a very disagreeable odor. In most cases the foetus is dead. When born alive, it is weak and puny, and usually dies or is destroyed within a few days. When the attendant fails to give the animal the necessary attention, or is careless in his manipulation of the parts, inflammation of the womb, caused by the decomposition of the retained membranes, or the introduction of irritating germs on the ropes, instruments and hands, may occur. Death commonly follows this complication.

It is very important that the infectious form be diagnosed early in the outbreak. For all practical purposes we are justified in diagnosing infectious abortion, if several animals in the herd abort, especially if it follows the introduction of new animals. Methods of serum diagnosis, the agglutination and complement-fixation tests, are now used in the diagnosis of this disease.

The preventive treatment of the accidental form consists in avoiding conditions that may result in this accident. Pregnant animals should not be exposed to injuries from other animals or from the surroundings. Animals which show a predisposition to abort should not be bred. We should see that all animals receive the necessary exercise and a proper ration.

If the animal indicates by her actions that abortion may take place, we should give her comfortable, quiet quarters. It is very necessary to keep her quiet, and if restless, morphine may be given. A very light diet should be fed and constipation prevented by administering a laxative. The necessary attention should be given in case abortion occurs.