Comstock—the same callow youth who had been charged with rifling Lucius' mail in the primitive New York City of 1851—came to the end of his long life in 1919. He was succeeded immediately by his son, William Henry II, who had only recently returned from military service during World War I. According to Mrs. Planty, former Morristown historian, "Young Bill" had been active in the business before the war and was making an inspection of the company's depots in the Orient, in the summer of 1914, when he was stranded in China by the cancellation of transpacific shipping services and was therefore obliged to cross China and Russia by the Transiberian Railway. This story, however, strains credulity a trifle, as the journey would have brought him closer to the scene of conflict at that time, and he was, in any event, only 17 years old when these events are supposed to have occurred.
The decline of the patent-medicine business was ascribed by Stewart Holbrook in his
Golden Age of Quackery
to three main factors: the Pure Food and Drug Acts; the automobile; and higher standards of public education. All of these were, of course, strongly in evidence by the 1920s, when William Henry Comstock II was beginning his career as the head of the Indian Root Pill enterprise. Nevertheless, the Morristown plant was still conducting a very respectable business at this time and was to continue for some four decades longer. The Comstock enterprise never seemed to have been much embarrassed by the muckraking attacks that surrounded the passage of the Federal Food and Drug Act of 1906. Aside from the enforcement of these measures by the energetic Harvey Wiley, the two most effective private assaults upon the patent-medicine trade probably were the exposures by Samuel Hopkins Adams in a series of articles in
Collier's
magazine in 1905-1906, under the title, "The Great American Fraud," and the two volumes entitled,
Nostrums and Quackery
, embodying reprints of numerous articles in the
Journal of the American Medical Association
over a period of years. Both sources named names fearlessly and described consequences bluntly. But the Comstock remedies, either because they may have been deemed harmless, or because the company's location in a small village in a remote corner of the country enabled it to escape unfriendly attention, seemed to have enjoyed relative immunity from these attacks. At least, none of the Comstock remedies was mentioned by name.[13] To be sure, these preparations—or at least those destined for consumption within the United States—had to comply with the new drug laws, to publish their ingredients, and over a period of time to reduce sharply the extensive list of conditions which they were supposed to cure. Nevertheless, it seems probable that the general change in public attitudes rather than any direct consequences of legislative enforcement caused the eventual demise of the Dr. Morse's Indian Root Pills.