677. Sex

Medicines for females should not be so strong as those for males, therefore it is advisable to reduce the doses about one-third.

678. Temperament

Persons of a phlegmatic temperament bear stimulants and purgatives better than those of a sanguine temperament, therefore the latter require smaller doses.

679. Habits

Purgatives never act so well upon persons accustomed to take them as upon those who are not, therefore it is better to change the form of purgative from pill to potion, powder to draught, or aromatic to saline. Purgatives should never be given when there is an irritable state of the bowels.

680. Use of Alcohol