There probably is every reason to think that, either by accident or design, a condition of greater or less insensibility to pain had been produced between 1820 and 1846, by a number of different people, educated and ignorant, but that no one had the originality or the hardihood to push these investigations to the point of determining the real usefulness of ether. This was partly from ignorance, partly from fear, and partly because of the generally accepted impossibility of producing safe insensibility to pain. So, while independent claims sprang up from various sources, made by aspirants for honors in this direction, it is undoubtedly as properly due to Morton to credit him with the introduction of this agent as an anesthetic as to credit Columbus with the discovery of the New World, in spite of certain evidences that some portions of the American continent had been touched upon by adventurous voyagers before Columbus ever saw it.

The noun "anesthesia" and the adjective "anesthetic" were suggestions of Dr. Oliver Wendell Holmes, who early proposed their use to Dr. Morton in a letter which is still preserved. He suggests them with becoming modesty, advises Dr. Morton to consult others before adopting them, but, nevertheless, states that he thinks them apt for that purpose. The word anesthesia, therefore, is just about of the same age as the condition itself, and it, too, deserves commemoration upon this occasion.

As one reads the history of anesthesia, which has been written up by a number of different authors, each, for the main part, having some particular object in view, or some particular friend whose claims he wishes especially to advocate, he may find mentioned at least a dozen different names of men who are supposed to have had more or less to do with this eventful discovery. But, for all practical purposes, one may reduce the list of claimants for the honor to four men, each of whose claims I propose to briefly discuss. These men were Long, Wells, Jackson and Morton. Of these four, two were dentists and two practising physicians, to whom fate seems to have been unkind, as it often is, since three of them at least died a violent or distressing death, while the fourth lived to a ripe old age, harassed at almost every turn by those who sought to decry his reputation or injure his fortunes.

Crawford W. Long was born in Danielsville, Ga., in 1816. In 1839 he graduated from the Medical Department of the University of Pennsylvania. In the part of the country where Long settled it was a quite common occurrence to have what were known as "ether frolics" at social gatherings, ether being administered to various persons to the point of exhilaration, which in some instances was practically uncontrollable. Long's friends claim that he had often noticed that when the ether effect was pushed to this extent the subjects of the frolic became oblivious to minor injuries, and that these facts, often noticed, suggested to his mind the use of ether in surgical operations. There is good evidence to show that Long first administered ether for this purpose on the 30th of March, 1842, and that on June 6th he repeated this performance upon the same patient; that in July he amputated a toe for a negro boy, but that the fourth operation was not performed until September of 1843. In 1844 a young man, named Wilhite, who had helped to put a colored boy to sleep at an ether frolic in 1839, became a student of Dr. Long's, to whom Long related his previous experiences. Long had never heard of Wilhite's episode, but had only one opportunity, in 1845, to try it, again upon a negro boy. Long lived at such a distance from railroad communication (130 miles) as to have few advantages, either of practice, observation or access to literature. Long made no public mention of his use of ether until 1849, when he published An Account of the First Use of Sulphuric Ether by Inhalation as an Anesthetic in Surgical Operations, stating that he first read of Morton's experiments in an editorial in the Medical Examiner of December, 1846, and again later; on reading which articles he determined to wait before publishing any account of his own discovery, to see whether anyone else would present a prior claim. No special attention was paid to Long's article, as it seemed that he merely desired to place himself on record. There is little, probably no reasonable doubt as to Long's priority in the use of ether as an anesthetic, although it is very doubtful if he carried it, at least at first, to its full extent. Nevertheless Long was an isolated observer, working entirely by himself, having certainly no opportunity and apparently little ambition to announce his discovery, and having no share in the events by which the value of ether was made known to the world. Long's strongest advocate was the late Dr. Marion Sims, who made a strong plea for his friend, and yet was not able to successfully establish anything more than has just been stated. As Dr. Morton's son, Dr. W. J. Morton, of New York, says, when writing of his father's claim: "Men used steam to propel boats before Fuller; electricity to convey messages before Morse; vaccine virus to avert smallpox before Jenner; and ether to annul pain before Morton."

But these men are not generally credited with their introduction by the world at large and, he argues, neither should Long or the other contestants be given the credit due Morton himself. In fact, Long writes of his own work that the result of his second experiment was such as to make him conclude that ether would only be applicable in cases where its effects could be kept up by constant use; in other words, that the anesthetic state was of such short duration that it was to him most unsatisfactory. Sir James Paget has summed up the relative claims of our four contestants in an article entitled Escape from Pain, published in the Nineteenth Century for December, 1879. He says:

"While Long waited, and Wells turned back, and Jackson was thinking, and those to whom they had talked were neither acting nor thinking, Morton, the practical man, went to work and worked resolutely. He gave ether successfully in severe surgical operations; he loudly proclaimed his deeds and he compelled mankind to hear him."

Horace Wells was born in Hartford, Vt., in 1815. In 1834 he began to study dentistry in Boston, and after completing his studies began to practise in Hartford, Ct. He was a man of no small ingenuity, and devised many novelties for his work. In December, 1844, he listened to a lecture delivered by Dr. Colton, who took for his subject nitrous oxide gas, the amusing effects of which he demonstrated to his audience upon a number of persons who visited the platform for that purpose. Wells was one of these. Wells, moreover, noticed that another young man, who bruised himself while under its influence, said afterward that he had not hurt himself at all. Wells then stated to a bystander that he thought that if one took enough of that kind of gas he could have a tooth extracted and not feel it. He at once called upon a neighboring dentist friend and made arrangements to test the anesthetic effects of the gas upon himself the next morning. Accordingly Colton gave him the gas, and Riggs, the friend, extracted the tooth; and Wells, returning to consciousness, assured them both that he had not suffered a particle of pain. He began at once to construct an apparatus for its manufacture. Dr. Marcey, of Hartford, then informed Wells that while a student at Amherst he and others had often inhaled nitrous oxide as well as the vapor of ether, for amusement, and suggested to Wells to try ether. After a few trials, however, it was found more difficult to administer, and Wells accordingly resolved to adhere to gas alone. This was in 1844, two years after Long's obscure experiments, of which, of course, they were ignorant. In 1845, Wells visited Boston for the purpose of introducing his discovery, and among others called upon his former partner, Morton, trying to establish the use of the gas. He soon became discouraged, however, and returned to Hartford, resuming his practice. There he continued to use gas for about two years, but failed to secure its introduction into general surgery, owing to prejudice and ignorance on the part of dentists and physicians alike.

Wells's claims have been advocated by many of his fellow-citizens, and in Bushnell Park, in Hartford, stands a monument erected by the city and the state, dedicated to Horace Wells, "who discovered anesthesia, November, 1844."

C. T. Jackson was born in Plymouth, Mass., in 1805. He graduated in the Harvard Medical School in 1829, after which he went abroad, where he remained for several years, made the acquaintance of the most distinguished men, experimented in general science, electricity and magnetism and even devised a telegraphic apparatus, similar to that which Morse patented a year later. Returning, in 1835, he opened in Boston a laboratory for instruction in analytical chemistry, the first of its kind in the country. He also made quite a reputation as a geologist and mineralogist and received official appointments from Maine, Rhode Island, New Hampshire and other states. In 1845 he discovered and opened up copper and iron mines in the Lake Superior district. In 1846 and 1847 he was much aroused by Morton's experiments with sulphuric ether, and claimed even that he had suggested the use of ether to Morton, claiming also that he had himself been relieved of an acute distress by inhalation of ether vapor, and that it was from reflection on the phenomena presented in his own case that the possibility of its use for relief of pain during surgical operations suggested itself to him. This led to a triangular conflict for the priority of discovery between Wells, Jackson and Morton, each claiming the honor for himself. Wells health soon gave way. He went abroad and got recognition from the French Institute and the Paris Academy of Sciences, which did not, however, endorse his claim as discoverer nor accept nitrous oxide as an anesthetic. Wells returned to find that Morton was on the tide of popular favor, the public having endorsed ether as the only reliable anesthetic. His mind became unbalanced, and in a fit of temporary aberration he ended his own life in a prison cell, in New York city in 1848.

Wells being out of the way, Jackson became Morton's most violent opponent, and the two indulged in a most bitter fight and unseemly discussion. A few years later, Jackson, who, as remarked, had an extensive acquaintance abroad, visited Europe and presented his claim to the credit of the discovery of ether before various individuals and learned bodies, and so well did he work upon the French Institute as to be recognized as the discoverer of modern anesthesia. A select committee of the House of Representatives, to whom in 1854 Congress referred the matter, announced the following conclusions: