The first college was founded in 1264 by Walter de Merton, former Chancellor to the King, at Oxford. A college had the living arrangements of a Hall, with the addition of monastic-type rules. A warden and about 30 scholars lived and ate meals together in the college buildings. Merton College's founding documents provided that: "The house shall be called the House of the Scholars of Merton, and it shall be the residence of the Scholars forever. . . There shall be a constant succession of scholars devoted to the study of letters, who shall be bound to employ themselves in the study of Arts or Philosophy, the Canons or Theology. Let there also be one member of the collegiate body, who shall be a grammarian, and must entirely devote himself to the study of grammar; let him have the care of the students in grammar, and to him also let the more advanced have recourse without a blush, when doubts arise in their faculty. . . There is to be one person in every chamber, where Scholars are resident, of more mature age than the others, who is to make his report of their morals and advancement in learning to the Warden. . . The Scholars who are appointed to the duty of studying in the House are to have a common table, and a dress as nearly alike as possible. . . The members of the College must all be present together, as far as their leisure serves, at the canonical hours and celebration of masses on holy and other days. . . The Scholars are to have a reader at meals, and in eating together they are to observe silence, and to listen to what is read. In their chambers, they must abstain from noise and interruption of their fellows; and when they speak they must use the Latin language. . . A Scrutiny shall be held in the House by the Warden and the Seniors, and all the Scholars there present, three times a year; a diligent enquiry is to be instituted into the life, conduct, morals, and progress in learning, of each and all; and what requires correction then is to be corrected, and excesses are to be visited with condign punishment. . ."

Issues frequently argued concerned the newly discovered philosophies of Aristotle vis a vis the accepted Christian philosophy. Aristotle emphasized the intellectual use of reason as a road to understanding whereas the church had always taught that understanding came from revelation by God.

Roger Bacon, an Oxford master, applied mathematical knowledge to natural phenomena such as metal work, mineral work, the making of weapons, agriculture, and the remedies and charms of wizards and magicians. He studied angles of reflection in plane, spherical, cylindrical, and conical mirrors, in both their concave and convex aspects. He did experiments in refraction in different media, e.g. air, water, and glass, and knew that the human cornea refracted light and that the human eye lens was doubly convex. (However it was another 400 years before the discovery of the image on the retina.) He comprehended the magnifying power of convex lenses and conceptualized the combination of lenses which would increase the power of vision by magnification. Soon afterwards, eyeglasses were available to correct farsightedness.

Bacon studied gravity and the propagation of force, specifically illustrated by the radiation of light and heat. He realized that rays of light pass so much faster than those of sound or smell that the time is imperceptible to humans. He knew that rays of heat and sound penetrate all matter without our awareness and that opaque bodies offered resistance to passage of light rays. This was the beginning of the science of physics.

He took the empirical knowledge as to a few metals and their oxides and some of the principal alkalis, acids, and salts to the abstract level of metals as compound bodies the elements of which might be separated and recomposed and the general concept of generation of liquids, gases, and solids, which was the beginning of the science of chemistry. He made experiments that led the way to saltpeter being made to explode, which led the way to the formulation of gunpowder. He believed that the principle of explosive energy would one day carry ships across the seas without sails and propel carriages down the streets, and flying machines. He knew the power of parabolic concave mirrors to cause parallel rays to converge after reflection to a focus and was familiar with work done to produce a mirror that would induce combustion at a fixed distance.

He studied man's physical nature, health, and disease, the beginning of the science of biology and medicine. He opined that the use of a talisman was not to bring about a change, but to bring the patient into a frame of mind more conducive to physical healing.

Bacon studied different kinds of plants and the differences between arable land, forest land, pasture land, and garden land.

Like other educated men of his day (and those of the 1200s through the 1500s), he believed that the earth was the center of the universe and in astrology, that is, that the position of the stars and planets influenced man and other earthly things. For instance, the position of the stars at a person's birth determined his character. The angle and therefore potency of the sun's rays influenced climate, temperament, and changes of mortal life such as disease and revolutions. There was a propitious time to have a marriage, go on a journey, make war, and take herbal medicine or be bled by leeches, the latter of which was accompanied by religious ceremony. Cure was by God, with medical practitioners only relieving suffering. Pressure and binding were applied to bleeding. Arrow and sword wounds to the skin or to any protruding intestine were washed with warm water and sewn up with needle and silk thread. Ribs were spread apart by a wedge to remove arrow heads. Fractured bones were splinted or encased in plaster. Dislocations were remedied. Hernias were trussed. Bladder stones blocking urination were pushed back into the bladder or removed through an artificial opening in the bladder.

Bacon studied the planetary motions and astronomical tables to forecast future events. He did calculations on days in a month and days in a year which later contributed to the legal definition of a leap year. He knew about magnetic poles attracting if different and repelling if the same and the relation of magnets' poles to those of the heavens and earth. He calculated the circumference of the world and the latitude and longitude of terrestrial positions, which was the beginning of the study of geography. He foresaw sailing around the world and pointed the way to the Copernican astronomy, which was founded on the concept of the earth and planets revolving around the sun.

His contribution to the development of science was abstracting the method of experiment from the concrete problem to see its bearing and importance as a universal method of research. He advocated changing education to include studies of the natural world using observation, exact measurement, and experiments.