Samuel Drew remained with his father's family from midsummer, 1782, till the autumn of the same year, and then took a situation in a shoemaker's shop at Millbrook, on the Cornish side of the estuary of the Tamar. After having been there for a year he moved to Cawsand and then to Crafthole, where he got mixed up in smuggling ventures.

Port Wrinkle, which Crafthole adjoins, lies about the middle of the extensive bay reaching from Looe Island to the Rame Head. It is little more than a fissure among the rocks which guard the long line of coast; and being exposed to the uncontrolled violence of the prevailing winds, affords a very precarious shelter.

Notice was given through Crafthole one evening, about the month of December, 1784, that a vessel laden with contraband goods was on the coast, and would be ready to discharge her cargo. At nightfall Samuel Drew, with the rest of the male population, made towards the port. One party remained on the rocks to make signals and dispose of the goods when landed; the other, of which he was one, manned the boats. The night was intensely dark; and but little progress had been made in discharging the vessel's cargo when the wind freshened, with a heavy sea. To prevent the ship being driven on to the rocks it was found expedient to stand off from the port; but this greatly increased the risk to those in the boats. Unfavourable as these circumstances were, all seemed resolved to persevere; and several trips were made between the vessel and the shore. The wind continuing to increase, one of the men in the boat with Drew had his hat blown off, and in leaning over the gunwale in his attempt to secure it, upset the boat, and three of the men were drowned. Samuel and two others clung to the keel for a time, but finding that they were drifting out to sea, they were constrained to let go and sustain themselves by swimming. But the night was pitch dark, and immersed in the waters they knew not in which direction to swim. Samuel had given himself up as lost, when he laid hold of a tangled mass of floating seaweed, and was able to sustain himself on that. At length he approached some rocks near the shore, upon which he and two other men, the only survivors of seven, managed to crawl; but they were so benumbed with cold and so much exhausted by their exertions that the utmost they could do was to cling to the rocks and let the sea wash over them. When a little recovered, they shouted for help, but the other boatmen were concerned in transporting their lading of kegs on shore, and not till the vessel had discharged all her cargo did they make any attempt to rescue the half-drowned men. Eventually they removed them to a farmhouse, where a blazing fire was kindled on the hearth and fresh faggots piled on it, while the half-drowned men, who were placed in a recess of the chimney, unable to relieve themselves, were compelled to endure the excessive heat which their companions thought was necessary to restore animation. The result was that they were half roasted. Samuel Drew says: "My first sensation was that of extreme cold. It was a long time before I felt the fire, though its effects are still visible on my legs, which are burnt in several places. The wounds continued open more than two years, and the marks I shall carry to my grave."

The death of his elder brother Jabez produced a profound impression on Samuel, and he became a Methodist.

"For the space of about four or five years I travelled through different parts of Cornwall, working whenever I could obtain employment; and during this period, waded through scenes of domestic distress, which can be interesting only to myself. Literature was a term to which I could annex no idea. Grammar I knew not the meaning of. An opportunity, however, now offering one an advance in wages at S. Austell, I embraced it, and came hither to work with rather an eccentric character. My master was by trade a saddler, had acquired some knowledge of book-binding, and hired me to carry on the shoe-making for him. My master was one of those men who will live anywhere, but get rich nowhere. His shop was frequented by persons of a more respectable class than those with whom I had previously associated; and various topics became alternately the subjects of conversation. I listened with all that attention which my labour and good manners would permit me, and obtained among them some little knowledge. About this time disputes ran high in S. Austell between the Calvinists and Arminians, and our shop afforded a considerable scene of action. In cases of uncertain issue, I was sometimes appealed to to decide upon a doubtful point. This, perhaps, flattering my vanity, became a new stimulus to action. I listened with attention, examined dictionaries, picked up many words, and, from an attachment which I felt to books that were occasionally brought to his shop to bind, I began to have some view of the various theories with which they abounded. The more, however, I read, the more I felt my own ignorance; and the more I felt my own ignorance, the more invincible became my energy to surmount it; and every leisure moment was now employed in reading one thing or other.... After having worked with this master about three years, I well recollect, a neighbouring gentleman brought Locke's Essay on the Human Understanding to be bound. I had never seen or heard of these books before. I took an occasion to look into them, when I thought his mode of reasoning very pretty and his arguments exceedingly strong. I watched all opportunities of reading for myself, and would willingly have laboured a fortnight to have had the books. They, however, were soon carried away, and with them all my future improvement by their means. I never saw his essay again for many years, yet the early impression was not forgotten, and it is from this accidental circumstance that I received my first bias for abstruse subjects.

"My master growing inattentive to his shoe-making trade, many of my friends advised me to commence business for myself, and offered me money for that purpose. I accepted the offer, started accordingly, and by mere dint of application, in about one year discharged my debts and stood alone. My leisure hours I now employed in reading, or scribbling anything which happened to pass my mind."

Thus he went on till 1798, when he laid the foundation of an Essay on the Immortality of the Soul. Whilst engaged upon this he had T. Paine's Age of Reason put into his hands. He read it, but saw the fallacy of many of his arguments, and he wrote his remarks on the book, and published them in pamphlet form at S. Austell in 1799.

Through this tract he obtained acquaintance with the Rev. John Whitaker, to whom he showed his MS. on The Immortality of the Soul, and was encouraged to revise, continue, and complete the essay, and it was published in November, 1802.

"During these literary pursuits I regularly and constantly attended on my business, and do not recollect that ever one customer has been disappointed by me through these means. While attending to my trade, I sometimes catch the fibres of an argument, which I endeavour to note the prominent features of, and keep a pen and ink by me for the purpose. In this state, what I can collect through the day remains on any paper which I have at hand till the business of the day is dispatched and my shop shut up, when, in the midst of my family, I endeavour to analyze, in the evening, such thoughts as had crossed my mind during the day."

At one time the bent of Drew's mind was towards astronomy, but when he considered how impossible it was for him, without means, to purchase a powerful telescope, to make any progress in the study of the stars, he abandoned the thought and devoted himself to metaphysics—perhaps one of the most unprofitable of all studies. His works were, however, read by some when they issued from the press, and are now no longer even looked into.