KEY: Isolation.
SYN: Segregation, detachment, disconnection, insularity, self-containedness.
ANT: Organization, co-membership, community, connection, concatenation, continuity.
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KEY: Issue.
SYN: Effect, outcome, manifestation, end, result, progeny, posterity, conclusion, consequence, upshot, children, offspring.
ANT: Cause, operation, working, principle, law, system, action, influence, origination, commencement, paternity, ancestry.
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KEY: Iteration.
SYN: Repetition, reiteration, harping, recurrence, succession.