2999. Climate.—The action of medicines is modified by climate and seasons. In summer, certain medicines act more powerfully than in winter, and the same person cannot bear the dose in July that he could in December.


3000. General Health.—Persons whose general health is good, bear stronger doses than the debilitated and those who have suffered for a time.


3001. Idiosyncrasy.—Walker will inform you that this long term means a peculiar temperament or disposition not common to people generally.


3002. For example, some persons cannot take calomel in the smallest dose without being salivated, or rhubarb without having convulsions; others cannot take squills, opium, senna, &c., therefore it is wrong to insist upon their taking these medicines.


3003. Forms best suited for Administration.—Fluids act quicker than solids, and powders sooner than pills.