The address is—

“To his much honoured friend Doctor Harvey one of his Majesty’s Physicians at his house in the Blackfriars be this delivered.”

The following is Harvey’s reply; it is written on the back of Dr. Ward’s letter:—

“Mr. Doctor Ward, I have showed to his Majesty this skull incrustated with stone which I received from you, and his Majesty wondered at it and looked content to see so rare a thing. I do now with thanks return it to you and your College, the same with the key of the case and the memorial you sent me enclosed herein, thinking it a kind of sacrilege not to have returned it to that place where it may for the instruction of men hereafter be conserved.”

The letter and skull have been preserved in a small ancient cabinet of carved oak, which stands in the Library of Sidney College. The skull is very curious. It is that of a young person and is encrusted with carbonate of lime, which is very hard and compact and is spread over the bone in such a manner as to resemble a petrification of the soft parts. The “note of the Donour” states that he was Captain William Stevens of Rotherhithe, one of the elder brethren of the Trinity, and that he brought the skull in 1627 from Crete where it was discovered about ten yards (circiter passus decem) below the surface of the ground in digging a well near the town of Candia.

Harvey’s pathological knowledge was sometimes called into use by the King as in the following case:—“A young nobleman, eldest son of the Viscount Montgomery,[12] when a child, had a severe fall attended with fracture of the ribs of the left side. The consequence of this was a suppurating abscess, which went on discharging abundantly for a long time, from an immense gap in his side: this I had from himself and other credible persons who were witnesses. Between the eighteenth and nineteenth years of his age, this young nobleman having travelled through France and Italy, came to London, having at this time a very large open cavity in his side, through which the lungs as it was believed could both be seen and touched. When this circumstance was told as something miraculous to his Serene Majesty King Charles, he straightway sent me to wait upon the young man, that I might ascertain the true state of the case. And what did I find? A young man, well grown, of good complexion and apparently possessed of an excellent constitution, so that I thought the whole story must be a fable. Having saluted him according to custom, however, and informed him of the King’s expressed desire that I should wait upon him, he immediately showed me everything, and laid open his left side for my inspection, by removing a plate which he wore there by way of defence against accidental blows and other external injuries. I found a large open space in the chest, into which I could readily introduce three of my fingers and my thumb: which done, I straightway perceived a certain protuberant fleshy part, affected with an alternating extrusive and intrusive movement: this part I touched gently. Amazed with the novelty of such a state, I examined everything again and again, and when I had satisfied myself, I saw that it was a case of old and extensive ulcer, beyond the reach of art, but brought by a miracle to a kind of cure, the interior being invested with a membrane and the edges protected with a tough skin. But the fleshy part (which I at first sight took for a mass of granulations, and others had always regarded as a portion of the lung) from its pulsating motions and the rhythm they observed with the pulse—when the fingers of one of my hands were applied to it, those of the other to the artery at the wrist—as well as from their discordance with the respiratory movements, I saw was no portion of the lung that I was handling, but the apex of the heart! covered over with a layer of fungous flesh by way of external defence as commonly happens in old foul ulcers. The servant of this young man was in the habit daily of cleansing the cavity from its accumulated sordes by means of injections of tepid water: after which the plate was applied, and with this in its place, the young man felt adequate to any exercise or expedition, and in short he led a pleasant life in perfect safety.

“Instead of a verbal answer, therefore, I carried the young man himself to the King, that his Majesty might with his own eyes behold this wonderful case: that, in a man alive and well, he might without detriment to the individual, observe the movement of the heart, and with his own hand even touch the ventricles as they contracted. And his most excellent Majesty, as well as myself, acknowledged that the heart was without the sense of touch: for the youth never knew when we touched his heart, except by the sight or sensation he had through the external integument.

“We also particularly observed the movements of the heart, viz., that in the diastole it was retracted and withdrawn: whilst in the systole it emerged and protruded: and the systole of the heart took place at the moment the diastole or pulse in the wrist was perceived; to conclude, the heart struck the walls of the chest and became prominent at the time it bounded upwards and underwent contraction on itself.”