From the determination of Almagro to conquer the country possessed by the Peruvians south of Cuzco, in consequence of the reports constantly received by himself and Pizarro, of the riches it contained, may be dated the discovery of Chili by Europeans.

Don Diego de Almagro de Malagon having collected a force of 570 Spaniards, and 15,000 Peruvians, set out from Cuzco, in the year 1535, attended by Paullu Inca, and choosing the road of the mountains, reached the province of Copiapo in Chili, after a march in which they had to contend with the Indians at every step; this, together with the inclemencies of the weather, the rugged nature of the road, and the winter overtaking them on the summit of the Andes, caused the death of 150 of the Spaniards and 10,000 of the Peruvians.

On the arrival of the army in Copiapo, Paullu Inca obliged the natives to deliver up all the gold in their possession, which amounting to the value of 500,000 ducats, he presented to Almagro.

The natives every where received the Spaniards with respect, amounting almost to adoration, as they imagined the new comers were a divine race sent by their gods to govern them, till after the arrival of Rodrigo Orgonez, with a reinforcement from Peru, when two of the soldiers committing acts of violence near the river Huasco, were slain by the people.

This, the first blood shed on either side, so irritated the Spaniards, that Almagro ordered the ulmen, his brother, and twenty of the chief people to be brought before him, when warning the natives to beware of similar transgressions, he committed his unfortunate victims to the flames; but the army disapproving of this cruel step, the affairs of Almagro soon became unprosperous.

At this juncture, Juan de Rada arrived with fresh troops from Peru, and with the letters of the king appointing Almagro governor of the territory south of that claimed by Pizarro. The Inca Paullu having reinforced his army with the Peruvian garrisons in Chili, Almagro penetrated as far south as the Rapel or Cachapoal, the boundary between the Independent Chilians and the Peruvian colonies: at this place the Inca endeavoured to persuade the general not to hazard an attack, as he was convinced, from what the Peruvians had experienced for a hundred years, that it would be unavailing; but Almagro persisted, a battle was fought, the Promaucians were victorious, and the Spaniards, disgusted with the event and with their general, returned to Peru, to which Almagro marched by the coast road through the desert of Atacama, and arrived near Cuzco, in 1538, with little loss; his subsequent history has been already related.

After the defeat and death of Almagro, Pizarro, wishing to extend his conquests, ordered Pedro de Valdivia to undertake an expedition to Chili with 200 Spaniards, a numerous body of Peruvians, women, monks and European quadrupeds, in order to settle such districts as he might deem proper.

Valdivia departed from Cuzco in 1540, and pursued the mountain road, taking the precaution of passing it in summer, on his arrival in Copiapo, so far from receiving the hospitable reception which Almagro met with, his army was attacked by the natives with great resolution, but as they had been too long in subjection to the Peruvians to be able to afford an effectual resistance, Valdivia soon reduced Copiapo, Coquimbo, Quillota and Melipilla, and with little loss arrived in the country of Mapocho, now called Santiago, where he laid the foundation of the city of Santiago, on the 24th of February, 1541.

The Promaucians assembling some forces to attack the Spaniards, Valdivia set out from Santiago to repel them, and left the new city in the care of Alonzo de Monroy; he was no sooner gone than the Mapochians attacked the place, and burning the settlement, forced the inhabitants to retire into the fort, but the commandant was relieved after a desperate siege by the return of Valdivia, who, hastening to the town, attacked the Mapochians and utterly defeated them.

During this attack a woman named Iñez Suarez killed several chieftains who were prisoners in the fort, with an axe; as she perceived they were about to take advantage of the distressed state of the Spaniards.