902. The veins which unite to form the vena portæ take up, by their capillary branches, certain portions of the contents of their respective organs, and bear those contents directly into the venous current. The capillary veins of the stomach take up certain parts of the contents of the stomach, it would appear the fluid substances received with the aliment more especially; the capillary veins of the duodenum take up certain portions of the contents of the duodenum, and so on of the capillary veins of the spleen, intestines, and all the organs whose veins combine to form the vena portæ. Further, branches of the absorbent vessels of these organs have been distinctly traced opening directly into the veins in their immediate neighbourhood. Certain products of digestion must, then, be constantly poured, both by the capillary veins and by the absorbent vessels of the digestive organs, into the blood of the vena portæ.
903. Accordingly, on the examination of animals soon after a meal, streaks of a substance like chyle are often observed in the blood of the vena portæ. It is further established by numerous experiments, that if alcohol, gamboge, indigo, and other odoriferous and colouring matters, are mixed with the food, their presence is manifest in the blood of the digestive organs, and more especially in the blood of the mesenteric veins and in that of the vena portæ, while no trace of these substances is ever found in the lacteals.
904. The lacteals, it has been shown (835. 1.), are special organs appropriated to the performance of a specific function, that of absorbing chyle. To fit them for this office, they are endowed with an elective power, by virtue of which they select, from the alimentary mass, that portion of it only which is converted into chyle; in a natural and healthy state they would appear to be incapable of absorbing any other substance excepting pure chyle. But in the digestive organs there is always present much nutritive matter not yet converted into proper chyle, and with this matter there are mixed foreign substances not strictly alimentary. These unassimilated matters and foreign substances, absorbed by the capillary veins or by the absorbent vessels, or by both, are conveyed directly into the vena portæ, by which vessel they are transmitted to the liver, where they undergo a true and proper digestion. After undergoing this digestion in the liver, they are sent by a short course to the heart, and thence to the lungs, where they are assimilated into, or at least commingled with, arterial blood, and, with arterial blood, are transmitted to the system. The substances subjected to this hepatic digestion, which is as real as that effected in the stomach and duodenum, do not appear to enter the lacteals at all; they have therefore a shorter course to traverse, and probably a proportionately less elaborate process to undergo, before their transmission to the lungs and their final entrance into the arterial system.
905. What the particular substances are for which this slighter digestive process suffices is not known with certainty. There is, however, reason to suppose that they consist chiefly of liquids, while there is direct evidence that vinous and spirituous liquids enter the system through this shorter course; since these fluids are often abundantly manifest in the blood of the vena portæ, when not the slightest trace of them can be detected in the lacteal vessels.
906. According to this view, the liver is a second digestive apparatus, completing what the first commences, or effecting what that is incapable of accomplishing; and this view assigns the reason why certain fluids taken into the stomach sometimes appear in the secretions and excretions with such astonishing rapidity; why the liver so constantly becomes diseased when highly stimulating substances, not properly alimentary, are mixed with the food, and more especially when ardent spirits or the stronger wines are largely and habitually taken; why the sympathy is so intimate and intense between the stomach and the liver and the liver and the stomach, both in health and disease; why in the ascending animal series the liver so soon appears after the stomach, and why the magnitude of the organ and the elaborateness of its structure progressively increase with the extension of the digestive apparatus and the corresponding complexity of the general organization.
907. The second function performed by the liver is that of excretion. The excrementitious matter eliminated from the blood by the liver is contained in its peculiar secretion, the bile. The bile consists of two portions, an assimilative part which combines chemically with the chyle, purifying and exalting its nature; and an excrementitious part which combines with the residue of the aliment.
908. The excrementitious part of the bile contains a large proportion of carbon and hydrogen. Carbon and hydrogen abound in venous blood; venous blood in large quantity is sent to the liver to afford the materials for the secretion of bile; consequently, the more copious the secretion of bile the greater the quantity of carbon and hydrogen abstracted from venous blood. It follows that, by this elimination of carbon and hydrogen from the blood, the liver is auxiliary, as an organ of excretion, to the skin and the lungs.
909. But it is well worthy of remark, that although the liver at all times assists the skin and the lungs in carrying on the process of excretion, it does this most especially under circumstances which necessarily enfeeble the action of the cutaneous and pulmonary organs.
910. Less carbon is expelled from the lungs in summer than in winter; at a high than at a low temperature; consequently by a long-continued exposure to intense heat, as in the hot months of summer, and still more by a continual residence in a warm climate, an accumulation of carbon in the blood is favoured. A part of this excess is removed by the increased exhalation from the skin. The skin, however, is the chief outlet, not for carbon, but for hydrogen; and accordingly by the increased perspiration hydrogen is largely removed. Hydrogen and carbon compose fat. The deposition of fat, could it go on to the requisite extent, would afford an adequate consumption for the superabundant carbon; but the formation of fat is prevented by the dissipation of the hydrogen. Under such circumstances, when the lungs cannot carry off the requisite quantity of carbon, nor the adipose tissue compensate for its diminished activity by the deposition of fat, the liver, taking on an increased action, secretes an extraordinary quantity of bile. In this manner the superfluous carbon, instead of being removed in the ordinary mode, by the pulmonary artery through the lungs, under the form of carbonic acid gas, is excreted by the vena portæ, through the liver, under the form of bile, while the superabundant hydrogen is removed by the increased quantity of perspiration; and thus the accumulation of these inflammable matters in the system is effectually prevented.
911. By the deposition of fat in the adipose tissue material assistance is afforded to the excretory action of the skin, the lungs, and the liver. Fat is composed essentially of carbon and hydrogen; it contains no nitrogen and very little oxygen. It is deposited whenever an excessive quantity of nutritive matter is poured into the blood, and especially when at the same time the different secretions and excretions ordinarily formed from the blood are diminished. The primary object of this deposition is to relieve the circulation of a load which would embarrass and ultimately stop the actions of life. It serves, however, a secondary purpose, that of forming a storehouse of nutritive matter, duly prepared for supplying the wants of the system, in case the body should be placed under circumstances in which the digestive organs can no longer receive food or no longer convert it into chyle.