Osmosis produces growths of great complexity, much more complicated indeed than the more simple forms of living organisms. This marvellous complexity of an osmotic growth may be compared with another fact, the ontogenetic development of the ovum, a single cell which under favourable conditions of environment may evolve into a most complicated organism. These considerations lead to the belief that the beginning of life has not been the production of a simple primitive form from which all others are descended, but that a number of such primitive forms may have been produced, forms which by a rapid physical development attained a high degree of complexity. Osmotic morphogenesis shows us that the ordinary physical forces have in fact a power of organization infinitely greater than has been hitherto supposed by the boldest imagination.

When we consider the ignorance in which we still remain as to the phenomena which pass before our very eyes, how can we expect to understand those which occurred in past ages, when the physical and chemical conditions were so immensely different from those which obtain in our own time? What do we know even now of the physical and chemical phenomena which take place in the unfathomed depths of the ocean, where for aught we know even at the present time the same

process may be going on—the genesis of life, and the emergence of living beings out of the inanimate mineral world? "Even now," says Albert Gaudry, "polyps and oceanic animalculæ are building up vast coral reefs and rocks. The oxygen and hydrogen which existed once was water, the oxygen and nitrogen which once made air, the carbon, the phosphorus, the silica and the lime which once were solid rock, now form the substance of living beings. The silica is deposited in the skeleton of a sponge or a radiolaria, the shell of a foraminifera or the carapace of a crustacean, or unites with phosphorus to form the bones of a vertebrate. A very tumult of life has succeeded to the primitive silence of inert matter. Life has invaded the earth, and we see on all sides the inanimate mineral kingdom being changed into a living world."

The admission that life may have appeared on the earth under the influence of natural forces and according to physical laws and conditions different from those of the present era throws a vivid light on the study of biogenesis, spontaneous generation, and evolution. The means of research are now indicated, and we have only to study the documents already in our possession in order to know the conditions which obtained when life first appeared on the globe. We must endeavour to reproduce these conditions and to study their effects.

Since all living beings are formed of the same elements as those of the mineral world, the term "organic" as applied to combinations can only be used in order to emphasize the complexity of their constitution. It was formerly believed that these organic combinations were the result of life, and could not be reproduced except by living organisms. To-day many of these organic substances are produced in the laboratory from inorganic materials. In the past history of the globe it is easy to imagine conditions which would facilitate the synthesis of organic substances without the interposition of life. At the temperature of the electric furnace, which was that of the earth at an early period of its evolution, chemical combinations are possible quite other than those obtaining under the present conditions of temperature and pressure. At the higher temperature of the early

geological era, silicides, carbides, phosphides, and nitrides were formed in stable combinations instead of the oxides, silicates, carbonates, phosphates, and nitrates of the present time. These combinations existed on the earth at a time when the conditions of temperature precluded the existence of water in a liquid state. As the temperature cooled, and the water vapour became condensed, it entered into chemical combination with the various rocks, producing organic compounds like acetylene, which results from the action of water on calcium carbide. H. Lénicque has developed a theory as to the formation of various rocks under these conditions, which he communicated in 1903 to the French Society of Civil Engineers.

The chemical evolution of the globe has undergone great changes as the temperature gradually fell and the constitution of its crust altered. As long as the temperature was higher than that at which water can exist, all chemical reactions must have taken place between anhydric substances, elements and salts in a state of fusion. These conditions are very different from those of the present-day chemistry, which is the chemistry of aqueous solutions. We may hope to be able to reproduce the earlier conditions by the experimental study of anhydric substances in a state of fusion.

At a later period, that of the primary and secondary rocks, there was a uniform and constant temperature of about 40° C. The atmosphere was charged with water vapour, and all the conditions were present for the production of storms and tempests. The atmosphere during long ages must have been the seat of formidable and incessant electric discharges; these discharges are the most powerful of all physical agents of chemical synthesis, and will cause nitrogen to combine directly to form various compounds—nitrates, cyanides, and ammonia. Carbonic acid would also be present in abundance and would enter into combination with these nitrogenous compounds. In this way we may imagine that compounds were formed which by some process of physical synthesis subsequently gave rise to vast quantities of albuminoid matter. At that time the seas and oceans contained all those substances which have

since been fixed by the metamorphism of the primitive rocks, or deposited in the sedimentary strata. Most of the elements in our minerals were formerly in a state of solution in these primeval seas, which contained carbonates, silicates, and soluble phosphates in great abundance. As the crust gradually cooled, the terrestrial atmosphere of necessity altered in composition, and the slow evolution of the atmosphere no doubt also exercised an influence on the development of living beings.

Palæontology teaches us that the earliest living organism appeared in the sea. The most ancient of living things, those of the primary ages, which were of greater duration than all other ages put together, were all aquatic. We find moreover that every living organism consists of liquids, solutions of crystalloids and colloids separated by osmotic membranes; and it is significant that the ocean, that vast laboratory of life, is also a solution of crystalloids and colloids. It is evident, then, that we must look to the study of solutions if we would hope to discover the nature and origin of life.