On leaving school the natural bent of his mind appeared to be for commercial pursuits. In order to prepare him for the path he had chosen, he was apprenticed to a merchant in London.

When Lewis reached manhood he came into possession of the little fortune left by his father, and thereupon resolved to engage in ventures on his own account. Perceiving that the old world did not present a suitable field of operation for a young man with a small capital, he anticipated the advice of the Sage of Chappaqua, and determined to seek his fortune in the new and promising western world. Collecting his effects together, he converted them into money, which he invested in such articles of merchandise as he thought marketable, and, with his stock in trade, sailed for New York, where he arrived in the spring of 1735. He was disappointed in finding that his stock of goods could not be sold in New York, by reason of the limited demand. A man of his energy was ready to overcome all difficulties. In the emergency he entered into a partnership with Edward Annesly, with whom he left a portion of his goods for sale, shipping the remainder to Philadelphia, whither he himself went to superintend their disposal. In the latter city he remained two years, and then returned to New York. Once more in New Amsterdam, he entered into business, becoming extensively engaged in foreign trade. While thus employed, and on June 15, 1745, realizing the truth of Scripture "that it is not good for man to be alone," he entered the holy and sacred relation of marriage with Miss Elizabeth Annesly, his partner's sister. The issue of this marriage was seven children, three only of whom survived infancy. One of his sons, Morgan Lewis, greatly distinguished himself, subsequently becoming governor of the State of New York.

During the remarkably severe winter of 1741 Lewis drove his horse and sleigh from New York to Barnstable, the entire length of Long Island Sound, on the ice. This must have been an interesting episode in his life. Referring to the intensity of the cold season, the "Boston Post" of January 12, 1741, says: "For these three weeks we have had a continued series of extreme cold weather, so that our harbors and rivers are continually frozen up. On Charles River a tent is erected for the entertainment of travellers. From Point Alderton, along the South Shore, the ice is continued for the space of above 20 miles."

The Boston "News Letter" of March 5, 1741, contains the statement that "people ride every day from Stratford, Conn., to Long Island, which is three leagues across, which was never known before."

It appears that the temperature did not moderate with the appearance of spring, as the same paper, on April 2, again alludes to the subject, saying, "that people from Thompson Island, Squantum, and the adjacent neighborhood have come fifteen Sabbaths successively upon the ice to our meeting."

Francis Lewis being an active and industrious man, his business often required his presence abroad, and led him to travel extensively in Europe. At various times he visited Russia, the Orkney and Shetland Islands, and on two occasions endured the terror and discomfort of shipwreck on the coast of Ireland.

On his return from the old world he found the affairs of the colony in a very unsettled condition. The French war was engaging the attention of the people. During a short period he was employed as agent to supply the wants of the British troops. The romance of his life was now about to commence. In the performance of his duties, he was present in August, 1756, when Fort Oswego was reduced, and compelled to surrender to the French General de Montcalm. The fort at this time was commanded by Colonel Mersey, one of his warm personal friends. In the emergency attending the bombardment, Lewis, to serve his friend, acted as his aid. Montcalm on the 10th of August approached the fort at the head of a mixed array of 5000 men, consisting of Europeans, Canadians, and Indians. The garrison having used up all their ammunition, Mersey spiked the cannon, and crossed the river to Little Oswego, without the loss of a single man. Montcalm at once took possession of the deserted fort, and immediately began a heavy fire, which was kept up without intermission. The next day Mersey was killed by a shot while standing by the side of Lewis. The commander having fallen, the garrison at once capitulated, surrendering themselves prisoners of war. It consisted of 1400 men, composing three regiments, one of which was the Jersey Blues, under Col. Peter Schuyler. By the terms of the surrender they were to be exempted from plunder, taken to Montreal, and treated with humanity. The French, however, did not regard the promise which they had made. When the surrender was effected, Montcalm soon forgot his pledge, and shamefully allowed one of the Indian warriors to select thirty of the prisoners to treat as he pleased. Lewis was one of the number chosen, and naturally expected a speedy and cruel death. He was, however, saved in a most unexpected manner. The family tradition on the subject, handed down by his son, and communicated to the writer by a gentleman of this city, who received it from Governor Morgan Lewis himself, is that Francis Lewis soon ascertained that he understood their dialect, and could freely converse with them, so that they comprehended what he said. His ability to communicate with the Indians in their own tongue pleased the chieftain, who extended to him the utmost kindness, and on his arrival at Montreal sought by every means within his power to induce the French commander to allow him to return to his family, without being compelled to pay any ransom. The request so urgently made was refused. Lewis was sent as a prisoner of war to France, and upon being exchanged was permitted to return to America.

The British government, in consideration of the services he had rendered, gave him a grant of 5000 acres of land, but as the fees amounted to more than the land was worth he never took out the necessary patent, the warrant for which was left in the Secretary of State's office.

Many have looked upon this tradition concerning Francis Lewis as mythical. Had it been false, a man of his sterling qualities would have contradicted the statements published during his lifetime. Some have supposed that he gathered more or less knowledge of the Indian dialect through business intercourse. It presents a very interesting feature in American history, opening up as it does a wide field for research. As it deserves more than a passing notice, it will not be out of place to turn aside for a moment, and consider how it was that Francis Lewis understood the Indian warrior.

It frequently has been claimed that Madoc, a Welshman, made voyages to America, long before Columbus was born. It has been conceded by many authorities that Prince Madoc, a Welsh navigator, upon the death of his father resolved to seek a new home, and thereby avoid contention with his brothers and relatives as to the succession. This was about the year 1170. He prepared his ships and munitions of war, and sailing westward came to a country theretofore unknown. Upon his return to his native land he gave a glowing account of the richness and beauty of the land he had visited. Restless in spirit, he could not long remain satisfied with the crags of Cambria, and prepared a fleet of ten sails, once more bent his course westward, and was never heard of again. There are many curious evidences that in early times Welsh tribes of Indians, or Indians speaking the Welsh language, were to be found on the continent of America.