3. Protection against Anopheles. Manson, in his Tropical Diseases (1905), says, "The question is often asked, Is there any other way by which malaria can be contracted than through a mosquito-bite? For many reasons, I believe not. It is difficult to prove a negative; but, so far, there is no observation capable of bearing investigation that would lead us to suppose that malaria can be acquired, under natural conditions, except by mosquito-bite," All authorities are agreed that, practically, the fight against malaria and the fight against Anopheles are one and the same thing; and the experiments by Sambon, Low, and Grassi, show what can be done, in this war against the mosquito, by way of defence. But what is practicable in Italy might not be generally practicable on the West African coast; as Sir William MacGregor says of Lagos:—

"It is not likely that in a place like Lagos as good results can be obtained from the use of mosquito-proof netting as in Italy. One great objection to it here is the serious and highly disagreeable way it checks ventilation. This is a difficulty that cannot be fully brought home to one in a cold climate. But, in a low-lying, hot, and moist locality like Lagos, it comes to be a choice of evils, to sit inside the netting stewed and suffocated, or to be worried and poisoned by mosquitoes outside. The netting is hardly a feasible remedy as regards native houses. It is not possible to protect even European quarters completely by it. Few officers or others are so occupied that they could spend the day in a mosquito-proof room. Certain it is that any man that suffers from the singular delusion that mosquitoes bite only during the night, would have a speedy cure by spending a few days, or even a few hours, in Lagos. Operations here (September 1901) are being limited to supplying one mosquito-proof room to the quarters of each officer. In this he will be able to spend the evening free from mosquitoes if he chooses to do so. The European wards of the hospital are similarly protected."

The European in Africa, as Ross says, is generally neglectful of his health; and the "unhealthiness" of the African coast is to some extent due to the life that men lead there:—

"Let us compare the habits of a European in a business-house in Calcutta with the habits of a European in West Africa. In Calcutta he sleeps under a punkah or mosquito-net, or both; he dresses and breakfasts under a punkah; in the evening he takes vigorous exercise, and he dines under a punkah. He wears the lightest possible clothing, he lives in a solid, cool, airy house, and he obtains very good food; once in five or six years, he returns to Europe for leave.... In Africa, the houses are frequently very bad; in Freetown, for instance, they are the same as the houses of natives, and are mingled with them. The Anglo-African seems to imagine that he can live in the tropics in the same manner as he lives in England. He seldom uses a punkah, except perhaps for an hour at dinner-time, and, not seldom, he neglects even the mosquito-net. The food is often, or generally, execrable. Owing to the frequent absence of gymkhanas and clubs, the exile obtains little suitable exercise."

But whatever risks the old resident may choose to take, the newcomer can at least use a proper and efficient mosquito-net at night, and avoid sleeping in a native house, and protect himself in these and the like ways against malaria.

4. The keeping down of Anopheles. The breeding places of Anopheles are ponds, swamps, and puddles, roadside ditches, tanks, and cisterns, old disused canoes, and the like collections of stagnant water: also the smaller receptacles that are more generally occupied by Culex, such as broken bottles, old tins, pots, and calabashes, and barrels, whatever will hold water—all the débris and broken rubbish round huts or houses. In all these places, Anopheles' eggs or larvæ are found; and, with practice, it is easy to detect them. Of course, it is not easy to wage war against the adult mosquito: the work is, Venienti occurrere morbo, to organise gangs of workmen, or of prison labour, and "mosquito brigades"; to clear the ground of cartloads of old biscuit-tins, broken gin-bottles, and other dust-heap things, in and around the place; to cover-in the cisterns, rain-barrels, and wells; to clean pools and duck-ponds of weed, and stock them with minnows; to put a film of kerosene to the puddles, or sweep them out, or fill them up and turf them over; everywhere, to drain, and level, and clean-up the surface soil; and everywhere, by these and the like methods, to break the cycle of the life of the plasmodium malariæ:—

"Draining and cultivation where the land will repay the expenditure, permanent and complete flooding where it will not, and such flooding is possible; proper paving of unhealthy towns, and the filling-in of stagnant, swampy pools; these—in other words, all measures calculated to keep down mosquitoes—are the more important things to be striven for in attempting the sanitation of malarious districts. In England, in Holland, in France, in Algeria, in America, and in many other places, enormous tracts of country, which formerly were useless and pestilential, have been rendered healthy and productive by such means." (Manson.)

And, short of such great enterprises as Government works of drainage, much has already been done, in many African towns, and in India, by the work of a few men and women: not only by practical sanitary improvements, but by insistent teaching and lecturing. For the admirable results recently obtained in Ismailia, Algeria, Formosa, and the Malay States, see the Medical Annual, 1905 and 1906.[39]

Before leaving the subject of malaria, it must be added that the discovery and study of the parasite which causes it have cleared up the mystery of the specific action of quinine upon the disease. It operates simply by its germicidal effect upon the microbe. But, beyond this, we have now a clue which we never had before to guide us to the most advantageous manner of administering the drug.

2. Yellow Fever