Graham’s work was mainly devoted to that section of the science now known as physical chemistry. His contributions to pure chemistry are few in number. By far the most important is his discovery of metaphosphoric acid and its relations to the other modifications of phosphoric acid. Ortho- or ordinary phosphoric acid was known to Boyle; pyrophosphoric acid was discovered by Clark. Graham’s work is noteworthy as first definitely indicating the inherent property of the acids to combine with variable but definite amounts of basic substances by successive replacement of hydroxyl groups—the property we now term basicity, and was of fundamental importance in regard to its bearing on the constitution of acids and salts.
Graham’s fame chiefly rests upon his discovery of the law of gaseous diffusion (1829–1831), upon his work on the diffusion of liquids, and upon his recognition of the condensed form of hydrogen he termed hydrogenium. Questions involving the conception of molecular mobility, indeed, constituted the main feature of his inquiries. We owe to him, among others, the terms crystalloid, colloid, dialysis, atmolysis, occlusion—all of which have taken a permanent place in the terminology of science.
Alexander William Williamson.
Alexander William Williamson was born at Wandsworth, London, on May 1, 1824. His father, a Scotchman and a fellow-clerk of James Mill (the father of John Stuart Mill) in the East India House, took an active share in the foundation, in 1826, of the University of London, subsequently known as University College. In 1840 the younger Williamson entered the University of Heidelberg with the intention of studying medicine; but, under the influence of Leopold Gmelin, he turned to chemistry. In 1844 he went to Giessen, to work under Liebig, and there made his first contributions to chemical science—viz., on the decomposition of oxides and salts by chlorine; on ozone; and on the blue compounds of cyanogen and iron. After graduating at Giessen he went, in 1846, to Paris, where he came under the influence of Comte, with whom he studied mathematics. In 1850, at Graham’s solicitation, he was appointed to the Chair of Practical Chemistry at University College, vacant by the death of Fownes. He at once embarked upon those researches which constitute his main contribution to science. In the attempt to build up the homologous series of the aliphatic alcohols from ordinary alcohol he succeeded in demonstrating the real nature of ether and its genetic relation to alcohol, and in explaining the process of etherification. The memoirs (1850–52) in which he embodied the facts had an immediate influence on the development of chemical theory. His explanation of the process of etherification familiarised chemists with the idea of the essentially dynamical nature of chemical change. He imported the conception of molecular mobility not only into the explanation of such metathetical reactions as the formation of the ethers, but into the interpretation of the phenomena of chemical change in general. In these papers, as also in one on the constitution of salts, published in 1851, he attempted to systematise the representation of the constitution and relations of oxidised substances—organic and inorganic—by showing how they may be regarded as built up upon the type of water considered as
H
O,
H
in which the hydrogen atoms are replaced, wholly or in part, by other chemically equivalent atoms. This idea was immediately adopted by Gerhardt, was further elaborated by Odling and Kekulé, and was eventually developed into a theory of chemistry.
Williamson continued to direct the laboratory of University College until 1887, when he retired to the country. He died at Hindhead on May 6, 1904.
Robert Wilhelm Bunsen was born at Göttingen on March 31, 1811, and after studying chemistry under Stromeyer, the discoverer of cadmium, went to Paris and worked with Gay Lussac. In 1836 he succeeded Wöhler as teacher of chemistry in the Polytechnic School of Cassel, and in 1842 became Professor of Chemistry in the University of Marburg. In 1852 he was called to Heidelberg, and occupied the Chair of Chemistry there until his retirement in 1889. He died at Heidelberg on August 16, 1899.
