Water 8.850
Fats and pigments soluble in petroleum ether 1.600
Fats and pigments soluble in chloroform 1.150
Odorous material and traces of tannin 5.022
Glucose 0.738
Gummy, mucilaginous and pectic matter 15.734
Soluble albuminoids and aleuron 6.536
Cellulose 7.434
Insoluble albuminose 2.216
Lignose 32.727
Fixed salts 17.976
Lost material .017
100.000

Previous to the studies of the above authors the seeds had been therapeutically tested by Delioux de Savignac and Professor Clouet. Heckel and Schlagdenhauffen have confirmed the febrifuge virtues of the seeds and are uncertain as to the active principle since they found no glucoside or alkaloid in their analysis. The antiperiodic properties are comparable with those of quinine and have even proved effective in some cases in which quinine failed. It seems quite clear that the tannin is the active principle which is the more probable because its anti-periodic virtues are now recognized by all therapeutists.

It is given in maceration or infusion, 2–15 grams of the seeds to 3 or 400 of water to be taken several times a day. The treatment causes no very marked physiological effects. It seems to act as a sedative to the nervous system.

Botanical Description.—An annual plant, .60–1 meter high. Root central with lateral rootlets. Stem straight, ramose. Leaves opposite, abruptly pinnate with a stylet in place of the odd leaflet. Leaflets, 5–6 pairs, the lower ones smaller, ovate, oblong, margins and lower face downy. Common petiole swollen at the base, 2 stipules and 1 glandule. Calyx, 5 unequal sepals. Corolla, 5 nearly equal petals, sulphur yellow, concave, the posterior one further developed. Two verticils of 5 stamens each. Of the 5 stamens superior to the sepals, 2 are fertile, larger and arched; of the other 5 stamens 4 are fertile and small. Pod compressed, linear, smooth, 5′ long, containing many compressed, heart-shaped seeds, separated by thin partitions.

Habitat.—Common in Luzon. Blooms in October.

Cassia alata, L.

Nom. Vulg.—Acapulco, Sp.-Fil.; Katandá, Gamut sa Buni, Sontig̃, Tag.; Suntig̃, Kansitás, Vis.; Pakayomkom-kastila, Pam.

Uses.—This is one of the most popular Philippine remedies and its usefulness is vouched for by many physicians practicing in many different lands. Its antiherpetic properties are notable and the Tagalo name of the plant, “Gamut sa Buni,” means literally “medicine for herpes.” The natives use the juice of the leaf applied locally to the affected part. These properties have long been familiar to the Malays and to the Hindoos who in their medical works give the plant the Sanscrit name of “Dadrughna,” meaning “to cure herpes.” The Pharmacopœia of Bengal recommends cassia in the form of an ointment made by mixing the crushed tender leaves with simple ointment. This preparation is, in our opinion, undesirable on account of its liability to become rancid and vaseline should be the excipient used. Another application for herpetic eruptions is the juice of the leaves mixed with an equal quantity of lemon juice. The Malays use the leaves dried in the sun, adding to them a little water and rubbing them briskly on the affected parts, the vigorous treatment being an important part of the cure.

The decoction of the leaves is a laxative and according to Mr. J. Wood the tincture has an action similar to that of senna. Dr. Pulney Andy of India states that the extract prepared from the tender leaves is a good substitute for extract of colocynth.

Mr. A. Porte claims to have obtained the best results with an acetic extract of the fresh leaves. The following is his formula: