"It may possibly seem, at first sight, that I am leading immediately away from the subject of the secondary action of alcohol. It is not so. I am leading directly to it. Upon all these membranous structures alcohol exerts a direct perversion of action. It produces in them a thickening, a shrinking and an inactivity that reduces their functional power. That they may work rapidly and equally, they require to be at all times charged with water to saturation. If, into contact with them, any agent is brought that deprives them of water, then is their work interfered with; they cease to separate the saline constituents properly; and, if the evil that is thus started, be allowed to continue, they contract upon their contained matter in whatever organ it may be situated, and condense it.
"In brief, under the prolonged influence of alcohol those changes which take place from it in the blood corpuscles, and which have already been described, extend to the other organic parts, involving them in structural deteriorations, which are always dangerous, and are often ultimately fatal."
ACTION OF ALCOHOL ON THE STOMACH.
Passing from the effect of alcohol upon the membranes, we come to its action on the stomach. That it impairs, instead of assisting digestion, has already been shown in the extract from Dr. Monroe, given near the commencement of the preceding chapter. A large amount of medical testimony could be quoted in corroboration, but enough has been educed. We shall only quote Dr. Richardson on "Alcoholic Dyspepsia:"
"The stomach, unable to produce, in proper quantity, the natural digestive fluid, and also unable to absorb the food which it may imperfectly digest, is in constant anxiety and irritation. It is oppressed with the sense of nausea; it is oppressed with the sense of emptiness and prostration; it is oppressed with a sense of distention; it is oppressed with a loathing for food, and it is teased with a craving for more drink. Thus there is engendered, a permanent disorder which, for politeness' sake, is called dyspepsia, and for which different remedies are often sought but never found. Antibilious pills—whatever they may mean—Seidlitz powders, effervescing waters, and all that pharmacopoeia of aids to further indigestion, in which the afflicted who nurse their own diseases so liberally and innocently indulge, are tried in vain. I do not strain a syllable when I state that the worst forms of confirmed indigestion originate in the practice that is here explained. By this practice all the functions are vitiated, the skin at one moment is flushed and perspiring, and at the next moment it is pale, cold and clammy, while every other secreting structure is equally disarranged."
TIC-DOULOUREUX AND SCIATICA.
Nervous derangements follow as a matter of course, for the delicate membranes which envelope and immediately surround the nervous cords, are affected by the alcohol more readily than the coarser membranous textures of other parts of the body, and give rise to a series of troublesome conditions, which are too often attributed to other than the true causes. Some of these are thus described: "The perverted condition of the membranous covering of the nerves gives rise to pressure within the sheath of the nerve, and to pain as a consequence. To the pain thus excited the term neuralgia is commonly applied, or 'tic;' or, if the large nerve running down the thigh be the seat of the pain, 'sciatica.' Sometimes this pain is developed as a toothache. It is pain commencing, in nearly every instance, at some point where a nerve is inclosed in a bony cavity, or where pressure is easily excited, as at the lower jawbone near the centre of the chin, or at the opening in front of the lower part of the ear, or at the opening over the eyeball in the frontal bone."
DEGENERATION OF THE LIVER.
The organic deteriorations which follow the long-continued use of alcoholic drinks are often of a serious and fatal character. The same author says: "The organ of the body, that, perhaps, the most frequently undergoes structural changes from alcohol, is the liver. The capacity of this organ for holding active substances in its cellular parts, is one of its marked physiological distinctions. In instances of poisoning by arsenic, antimony, strychnine and other poisonous compounds, we turn to the liver, in conducting our analyses, as if it were the central depot of the foreign matter. It is, practically, the same in respect to alcohol. The liver of the confirmed alcoholic is, probably, never free from the influence of the poison; it is too often saturated with it. The effect of the alcohol upon the liver is upon the minute membranous or capsular structure of the organ, upon which, it acts to prevent the proper dialysis and free secretion. The organ, at first, becomes large from the distention of its vessels, the surcharge of fluid matter and the thickening of tissue. After a time, there follows contraction of membrane, and slow shrinking of the whole mass of the organ in its cellular parts. Then the shrunken, hardened, roughened mass is said to be 'hob-nailed,' a common, but expressive term. By the time this change occurs, the body of him in whom it is developed is usually dropsical in its lower parts, owing to the obstruction offered to the returning blood by the veins, and his fate is sealed.... Again, under an increase of fatty substance in the body, the structure of the liver may be charged with, fatty cells, and undergo what is technically designated fatty degeneration."