Things remaining in this state, I inoculated him again on the 30th in the morning, being the eighth day from the first inoculation. On the evening of the same day he complained of chilliness, attended with pain in his head and limbs, and passed an uneasy night. These complaints lasted in a very moderate degree for two days more, but without the least appearance of a fever. A very few pimples were discovered upon the decline of these symptoms, but they soon vanished without maturating.
CASE III.
Nov. 23d.] A third patient, a young man twenty years of age, was inoculated with the two last. I had not seen his arm from the time he was inoculated to the 28th, when he came to the house in company with the others. He said the incised part had itched very much the first three or four days, but it now appeared nearly in the same state as the preceding.
He was also inoculated again on the 30th. But as the succeeding complaints, and doubtful eruption in this case, bore an exact resemblance to those of the former, it is needless to repeat them.
Nothing happened to either from the second inoculation.
CASE IV.
1765, May 5th.] A man aged twenty-four was inoculated; after which he went to visit a relation, till it should be thought proper for him to come to the house, which I directed him to do on the 11th, if he should continue well till that time.
He took with him two calomel pills, one of five and the other of ten grains. He was ordered to take the least on the 8th, the other on the following night, and an ounce of purging salts the next morning.
I did not see him till the 11th, when he came to the house: he was then perfectly well, but said he had been a little giddy for the last day or two, and that his head had ached very much the preceding day for about an hour, insomuch that he thought he must have come over; that his arm had itched very much, and the purge had worked very briskly.