This lecture is published almost verbatim as it was delivered. On this account the experiments mentioned are not minutely described, the reader being supposed to see them performed.

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A LECTURE, &c.

THE greatest blessing we enjoy is health, without it, wealth, honors, and every other consideration, would be insipid, and even irksome; the preservation of this state therefore, naturally concerns us all. In this lecture, I shall not attempt to teach you to become your own physicians, for when the barriers of health are once broken down, and disease has established itself, it requires the deepest attention, and an accurate acquaintance with the extensive science of medicine, to combat it; to attain this knowledge demands the labour of years. But, a majority of the diseases to which we are subject, are the effects of our own ignorance or imprudence, and it is often very easy to prevent them; mere precepts however, have seldom much effect, unless the reasoning upon them be rendered evident; on this account, I shall first endeavour, in as plain and easy a manner as possible, to explain to you the laws by which life is governed; and when we see in what health consists, we shall be better enabled to take such methods as may preserve it. Health is the easy and pleasant exercise of all the functions of the body and mind; and disease consists in the uneasy and disproportioned exercise of all, or some of the functions.

When dead matter acts upon dead matter, the only effects we perceive are mechanical, or chemical; for though there may appear to be other kinds of attraction, or repulsion, such as electric and magnetic, yet these come under the head of mechanical attraction, as producing motion; we may therefore lay it down as a law, that when dead, or inanimate bodies act upon each other, no other than mechanical, or chemical effects are produced; that is, either motion, or the decomposition, and new combination of their parts. If one ball strike another, it communicates to it a certain quantity of motion, this is called mechanical action; and if a quantity of salt, or sugar, be put into water, the particles of the salt or sugar will separate from each other, and join themselves to the particles of the water; the salt and water in these instances, are said to act on each other chemically; and in all cases whatever, in which inanimate, or dead bodies act on each other, the effects produced are, motion, or chemical attraction.

But, when dead matter acts on those bodies which we call living, the effects are much different; let us take for example a very simple instance.—Snakes, at least some species of them, pass the winter in a torpid state, which has all the appearance of death; now heat, if applied to dead matter, will only produce motion, or chemical combination; but if it be applied to the snake, let us see what will be the consequence; the reptile first begins to move, and opens its eyes and mouth; when the heat has been applied for some time, it crawls about in search of food, and performs all the functions of life. Here then, dead matter, when applied to a living body, produces living functions; for if the heat had not been applied, the snake would have continued senseless, and apparently lifeless. In more perfect animals, the effects produced by the action of dead matter on them, are more numerous, and are different in different living systems, but are in general the following—sense and motion in almost all animals, and in many the power of thinking, and other affections of the mind. The powers, or dead matters, which are applied, and which produce these functions, are chiefly, heat, food, and air. The proof that these powers do produce the living functions, is in my opinion a very convincing one, namely, that when their actions are suspended, the living functions cease; take away, for instance, heat, air, and food from animals, and they soon become dead matter, and it is not necessary that an animal should be deprived of all these to put a stop to the living functions; if any one of them be taken away, the body sooner or later becomes dead matter: it is found by experience, that if a man be deprived of air, he dies in about three or four minutes; for instance, if he be immersed under water; if he be deprived of heat, or in other words, exposed to a very severe degree of cold, he likewise soon dies; or if he be deprived of food, his death is equally certain, though more slow. It is sufficiently evident then, that the living functions are owing to the action of these external powers upon the body. What I have here said, is not confined to animals, but the living functions of vegetables are likewise caused by the action of dead matter upon them. The dead matters, which by their action produce these functions, are principally heat, moisture, light, and air. It clearly follows therefore, from what I have said, that living bodies must have some property different from dead matter, which renders them capable of being acted upon by these external powers, so as to produce the living functions; for if they had not, the only effects which these powers could produce, would be mechanical, or chemical. Though we know not exactly in what this property consists, or in what manner it is acted on, yet we see, that when bodies are possessed of it, they become capable of being acted upon by external powers, and thus the living functions are produced; we shall therefore call this property excitability, and in using this term it is necessary to mention, that I mean only to express a fact, without the least intention of pointing out the nature of that property which distinguishes living from dead matter, and in this we have the example of the great Newton, who called the property which causes bodies in certain situations to approach each other, gravitation, without in the least hinting at its nature; yet, though he knew not what gravitation was, he investigated the laws by which bodies were acted on by it, in the same manner, though we are ignorant of excitability, or the nature of that property which distinguishes living from dead matter, we can investigate the laws by which dead matter acts on living bodies through this medium. We know not what magnetic attraction is, and yet we can investigate its laws; the same holds good with regard to electricity; if we ever should attain a knowledge of the nature of this property, it would make no alteration in the laws which we had before discovered.

I shall now proceed to the investigation of the laws by which the excitability is acted on; but I must first define some terms which it will be necessary to use, to avoid circumlocution, and at the same time to give us more distinct ideas on the subject.

When the excitability is in such a state as to be very susceptible of the action of external powers, I shall call it abundant, or accumulated; but when it is found not very capable of receiving their action, I shall say, it is deficient, or exhausted. I would not wish however, to have it thought, that by these terms I mean in the least to hint at the nature of excitability, nor that it is really one while increased, and at another diminished in quantity, for the abstract question is in no shape considered; we know not whether the excitability, or the vital principle, depends on a particular arrangement of matter, or from whatever cause it may originate; by the terms here used, I mean only to say, that the excitability is easily acted on when I call it abundant, or accumulated; at other times the living body is with more difficulty excited, and then I say, the vital principle is deficient, or exhausted.

The laws by which external powers act on living bodies, will, on a careful examination, be found to be the following—

First, when the powerful action of the exciting powers ceases for some time, the excitability accumulates, or becomes more capable of receiving their action, and is more powerfully affected by them.