The immoderate use of spirituous and fermented liquors, is still more destructive of the digestive powers of the stomach; but this will be better understood, when we have examined the laws by which external powers act upon the body. The remarks I have made could not, however, I think, have come in better, than immediately after our examination of the structure of the digestive organs, as the impropriety of intemperance, with respect to food, is thus rendered more evident.

The appetite becomes deficient from want of exercise, independently of the other causes that have been mentioned. Of all the various modes of preserving health, and preventing diseases, there is none more efficacious than exercise; it quickens the motion of the fluids, strengthens the solids, causes a more perfect sanguification in the lungs, and, in short, gives strength and vigour to every function of the body. Hence it is, that the Author of nature has made exercise absolutely necessary to the greater part of mankind for obtaining means of existence. Had not exercise been absolutely necessary for our well being, says the elegant Addison, nature would not have made the body so proper for it, by giving such an activity to the limbs, and such a pliancy to every part, as necessarily produce those compressions, extensions, contortions, dilatations, and all other kinds of motion, as are necessary for the preservation of such a system of tubes and glands.

We may, indeed, observe, that nature has never given limbs to any animal, without intending that they should be used. To fish she has given fins, and to the fowls of the air wings, which are incessantly used in swimming and flying; and if she had destined mankind to be eternally dragged about by horses, her provident economy would surely have denied them legs.

The appetite becomes deficient on the commencement of many diseases, but this is to be looked upon here rather as a salutary than as a morbid symptom, and as a proof that nature refuses the load, which she can neither digest nor bear with impunity.

In healthy people the appetite is various, some requiring more food than others; but it sometimes becomes praeternaturally great, and then may be regarded as a morbid symptom. The appetite may be praeternaturally increased, either by an unusual secretion of the gastric juice, which acts upon the coats of the stomach, or by any acrimony, either generated in, or received into the stomach, or, lastly, by habit, for people undoubtedly may gradually accustom themselves to take more food than is necessary.

The appetite sometimes becomes depraved, and a person thus affected, feels a desire to eat substances that are by no means nutritious, or even esculent: this often depends on a debilitated state of the whole system. There are some instances, however, in which this depravity of the appetite is salutary; for example, the great desire which some persons, whose stomachs abound with acid, have for eating chalk, and other absorbent earths: likewise, the desire which scorbutic patients have for grass, and other fresh vegetables. Appetites of this kind, if moderately indulged in, are salutary, rather than hurtful.

The appetite for liquids as well as solids is sometimes observed to be deficient, and sometimes too great. The former can scarcely be considered as a morbid symptom, provided the digestion and health be otherwise good. But when along with diminished thirst, the fauces and tongue are dry, this deficiency may be regarded as a morbid and dangerous symptom.

A more common morbid symptom, however, is too great thirst, which may arise from a deficiency of fluids in the body, produced by violent exercise, perspiration, too great a flow of urine, or too great an evacuation of the intestines. A praeternatural thirst may likewise arise from any acrid substance received into the stomach, which our provident mother, nature, teaches us to correct by dilution; this is the case with respect to salted meats, or those highly seasoned with pepper. It may arise also from the stomach being overloaded with unconcocted aliment, or from a suppressed or diminished secretion of the salivary liquors in the mouth, which may arise from fever, spasm, or affections of the mind; an increased thirst may likewise take place, from a derivation or determination of the fluids to other parts of the body; of this, dropsy affords an example. Indeed, various causes may concur to increase the thirst; this is the case in most fevers, where great thirst is occasioned by the dissipation of the fluids of the body by heat, as well as by the diminished secretion of the salivary humours which should moisten the mouth; to which may be added, the heat and diminished concoctive powers of the stomach.

From what has been said, we can easily understand, why praeternatural thirst may sometimes be a necessary instinct of nature, at other times, an unnecessary craving; why acids, acescent fruits, and weak fermented liquors quench thirst more powerfully than pure water; and lastly, why thirst, in some instances, may be relieved by emetics, when it has resisted other remedies.

There is no organ of the body whose functions are so easily deranged as those of the stomach; and these derangements prove a very fertile source of disease; they ought, therefore, carefully to be guarded against; and it is fortunate for us that we have this generally in our power, if we would but avail ourselves of it: for most of the derangements proceed from the improper use of food and drink, and a neglect of exercise. Indeed, when we examine, we shall find but a short list in the long catalogue of human diseases, which it is not in our power to guard against and prevent: and which surely will be guarded against, when their causes are known, and consequences understood.