The first observation which strikes us, is that of the very different effects that are produced when inanimate bodies act on each other, and when they exert their action on living matter.
When dead matter acts upon dead or inanimate matter, the only effects we perceive are mechanical, or chemical; that is, either motion, or the decomposition and new combination of their parts. If one ball strikes another, it communicates to it a certain quantity of motion, this is called mechanical action; and if a quantity of salt, or sugar, be put into water, the particles of salt, or sugar, will separate from each other, and join themselves to the particles of the water; these substances in these instances are said to act chemically on each other, and in all cases whatever, in which inanimate or dead bodies act on each other, the effects produced are motion, or chemical attraction; for though there may appear to be other species of action which sometimes take place, such as electric and magnetic attraction and repulsion, yet these are usually referred to the head of mechanical action or attraction.
But when dead matter acts upon those bodies we call living, the effects produced are much different. There are many animals which pass the winter in a torpid state which has all the appearance of death; and they would continue in that state, if deprived of the influence of heat; now heat if applied to dead matter, will only produce motion, or chemical combination: in fluids it produces motions by occasioning a change in their specific gravity; and we know that it is one of the most powerful agents in chemical combination and decomposition; but these are the only effects it produces when it acts upon dead matter. But let us examine its effects when applied to living organized bodies. Bring a snake or other torpid animal into a moderately warm room, and observe what will be the consequence. After a short time the animal begins to move, to open its eyes and mouth; and when it has been subject to the action of heat for a longer time, it crawls about in search of food, and performs all the functions of life.
Here then, dead matter, when applied to the living body, produces the living functions, sense and motion: for if the heat had not been applied, the animal would have continued senseless, and apparently lifeless.
In more perfect animals, the effects produced by the action of dead matter upon them, are more numerous, and are different in different living systems; but are in general the following; sense and motion in almost all animals, and in many the power of thinking, and other affections of the mind.
The powers, or dead matters, which by their action produce these functions, are chiefly heat, food, and air. The proof that these powers do produce the living functions is in my opinion very satisfactory, for when their action is suspended, the living functions cease. If we take away, for instance, heat, air, and food, from animals, they soon become dead matter. This is as strong a proof that these matters are the cause of the functions, as that heat is the cause of the expansion of bodies, when we find that by withdrawing it the expansion ceases. Indeed it is not necessary that an animal should be deprived of all these powers to put a stop to the living functions; if any one of them is taken away, the body sooner or later becomes dead matter: it is found by experience, that if a man is deprived of air, he dies in about three or four minutes; for instance, if he is immersed under water: if he is deprived of heat, or in other words is exposed to a very severe degree of cold, he likewise soon dies; or if he is deprived of food, his death is equally certain, though more slow; it is sufficiently evident then that the living functions are owing to the action of these external powers upon the body.
What I have here said is not confined to animals, but the living functions of vegetables are likewise caused by the action of dead matter upon them. The powers, which by their actions produce the living functions of vegetables, are principally heat, moisture, light, and air.
From what has been said, it clearly follows, that living bodies must have some property different from dead matter, which renders them capable of being acted on by these external powers, so as to produce the living functions; for if they had not, it is evident that the only effects which these powers could produce, would be mechanical, or chemical.
Though we know not exactly in what this property consists, or in what manner it is acted on, yet we see that when bodies are possessed of it, they become capable of being acted on by external powers, so as to produce the living functions.
We may call this property, with Haller, irritability, or, with Brown, excitability; or we may use vital principle, or any other term, could we find one more appropriate. I shall use the term excitability, as perhaps the least liable to exception, and in using this term, it is necessary to mention that I mean only to express a fact, without the smallest intention of pointing out the nature of that property which distinguishes living from dead matter; and in this we have the illustrious example of Newton, who called that property which causes bodies in certain situations to approach each other, gravitation, without in the least hinting at its nature. Yet though he knew not what gravitation was, he investigated the laws by which bodies were acted on by it, and thus solved a number of phenomena which were before inexplicable: in the same manner, though we are ignorant of the nature of excitability, or of the property which distinguishes living from dead matter, we can investigate the laws by which dead matter acts upon living bodies through this medium. We know not what magnetic attraction is, yet we can investigate its laws: the same may be observed with respect to electricity. If ever we should obtain a knowledge of the nature of this property, it would make no alteration in the laws which we had before discovered.