This is not merely a useless physiological disquisition; it is of the greatest use in directing our practice; and teaches us that, in passive inflammation, which has all the symptoms of active, and therefore shows in a striking point of view the fallacy of symptoms, we shall not succeed by applying leeches, and other debilitating means, to the inflamed part; on the contrary, we shall aggravate the complaint; and the cure must be effected by stimulants applied to the part.

As an instance of this kind of inflammation, I may mention that kind of ophthalmia or inflammation of the eyes, which is of long standing, and which not only resists the powers of leeches and blisters, but is increased by them. I have frequently been consulted by patients, who had for months been under the debilitating plan, without any benefit; and who have been relieved almost instantly by the application of electricity and a stimulating lotion, which restored the tone of the debilitated vessels of the sclerotic coat, and enabled them to expel their overcharged contents; and the balance between their action and the propelling force being restored, the inflammation disappeared.

Indeed the effects of electricity in these kinds of inflammations are wonderful: it seems to act almost by a charm, so quickly does the inflammation subside; but when we understand the nature of this kind of inflammation, it is nothing but what we might expect from its action.

I have been thus minute on the subject of inflammation, because the theory of it, which I have attempted to defend, differs considerably from the commonly received opinions. I shall now proceed to consider the nature of asthenic diseases.

From what has been already said, it must be evident that the causes of diseases which we have assigned, are very different from those delivered by physicians who preceded Dr. Brown. Some physicians imagined that diseases were caused by a change in the qualities of the fluids, which became sometimes acid, and sometimes alkaline; or on a change of figure of the particles of the blood: some imagined diseases to be owing to a rational principle, which they called the vis medicatrix naturae, which governed the actions of the body, and excited fever or commotion in the system to remove any hurtful cause, or expel any morbid matter, which might have insinuated itself into the body. Others supposed many diseases to arise from a constriction of the extreme vessels by cold; or from a spasm of them, which was a contrivance of the vis medicatrix, to rouse the action of the heart and arteries to remove the debility induced.

We have seen, however, that health and diseases are the same state, and depending upon the same cause; viz. excitement, but differing in degree; and that the powers producing both are the same, sometimes acting with a proper degree of force: at other times either with too much, or too little.

We shall now examine how the diminished actions of the different exciting powers produce asthenic disease; and we shall take them in the same order as when we were speaking of sthenic diseases. It must be recollected however that an asthenic state, or a state of debility, may be produced in two ways. First, by directly diminishing the action of the exciting powers. Secondly, by exhausting the excitability, by a strong or long continued stimulant action. The former state is called direct debility, and the latter indirect debility. This is not merely a distinction without a difference, the body is in very different states, under these two different forms of disease. In the former case, the excitability is abundant, and highly susceptible of the action of stimulants. In the latter, it is exhausted, and the body has very little susceptibility.

Cold, or a diminution of heat, carried beyond a certain degree, is unfriendly to all animals. Dr. Beddoes has shown very clearly in his Hygeia, that it is the cause of a great many diseases which take place at boarding schools, and that it there gives origin to a great number of diseases that afterwards arise, and, indeed, not unfrequently ruins the constitution. It produces relaxation of the vessels, asthenic or passive inflammation, and even gangrene. He has shown that in most schools children are afflicted with chilblains from this cause; this is a case of passive inflammation, but is only a symptom of the general debility induced, which shows itself afterwards by the production of other symptoms. Hence it is necessary for the preservation of health, that the temperature of school rooms should always be kept equable, and regulated by means of a thermometer. It should not exceed 50 degrees, nor should it be allowed to fall much below it. If precautions of this kind are thought to be necessary, and practised with uncommon attention, in places where vegetables are reared, surely they ought not to be neglected in those seminaries where the human species are to be brought to maturity, and a good constitution established.

But though I have no doubt whatever, that this equable temperature would prevent a number of diseases, which originate in too low a temperature, yet I am far from wishing to have it thought that I would not induce a hardy state of the constitution, which would enable it to bear the vicissitudes to which it must be exposed in its journey through life, by every means in my power. Hardiness is the most enviable of all the attributes of animal nature, and can neither be acquired, nor recovered when it is lost, but upon certain terms, to which many people submit with reluctance, because they must give up many indulgences and gratifications with which it is utterly inconsistent.

One of the causes that chiefly contributes to reduce persons living in affluence below the standard of hardiness, is the dependence they place on a considerable degree of external warmth, for preserving a comfortable state of sensation. From what has been said again and again in some of the latest of these lectures, it must be evident that continued warmth renders the living system less capable of being excited to strong, healthy, and pleasant action: heat in excess, whether it may be excess of duration or intensity, constantly debilitates, by exhausting the excitability of the system, and thus producing a state of indirect debility. Every muscle steeped in a heated medium, whether of air or water, loses much of its contractibility. A heart kept in heated air, or put in hot water, will not contract on the application of a stimulus; even the limb of a frog, when heated in this manner, ceases to move on the application of the galvanic exciters. Every nerve grows languid, and when it does become excited, it acquires a disposition to throw the moving fibres, with which it is connected, into starts, twitchings, and other irregular convulsive motions. Though therefore nothing can more contribute to the health of the body than a moderate and well regulated temperature, about 48 or 50 degrees, sometimes for a short interval a little lower, when exercise is taken at the same time, yet when we consider the life led by persons of fashion, we should hope that it proceeded from ignorance of these consequences; so diametrically opposite is it to the dictates of nature and reason.