Meanwhile at Ste Marie Ragueneau and his companions learned from Huron fugitives of the fate of their comrades; and waited, hourly expecting to be attacked. The priests were attended by about twoscore armed Frenchmen. All day and all night the anxious fathers prayed and stood on guard. In the morning three hundred Huron warriors came to their relief, bringing the welcome news that the Hurons were assembling in force to give battle to the invaders. These Hurons were just in time to fall in with a party of Iroquois, already on the way to Ste Marie. An encounter in the woods followed. At first some of the Hurons were driven back; but straight-away others of their band rushed to the rescue; and the Iroquois in turn ran for shelter behind the shattered palisades of St Louis. The Hurons followed, and finally put the enemy to rout and remained in possession of the place.

Now followed an Indian battle of almost unparalleled ferocity. Never did Huron warriors fight better than in this conflict at the death-hour of their nation. Against the Hurons within the palisades came the Iroquois in force from St Ignace. All day long, in and about the walls of St Louis, the battle raged; and when night fell only twenty wounded and helpless Hurons remained to continue the resistance. In the gathering darkness the Iroquois rushed in and with tomahawk and knife dispatched the remnant of the band.

But the Iroquois had no mind for further fighting, and did not attack Ste Marie. They mustered their Huron captives—old men, women, and children—tied them to stakes in the cabins of St Ignace, and set fire to the village. And, after being entertained to their satisfaction by the cries of agony which arose from their victims in the blazing cabins, they made their way southward through the forests of Huronia and disappeared.

Panic reigned throughout Huronia. After burning fifteen villages, lest they should serve as a shelter for the Iroquois, the Hurons scattered far and wide. Some fled to Ste Marie, some toiled through the snows of spring to the villages of the Petuns, some fled to the Neutrals and Eries, some to the Algonquin tribes of the north and west, and some even sought adoption among the Iroquois. Ste Marie stood alone, like a shepherd without sheep: mission villages, chapels, residences, flocks—all were gone. The work of over twenty years was destroyed. Sick at heart, Ragueneau looked about him for a new situation, a spot that might serve as a centre for his band of devoted missionaries as they toiled among the wanderers by lake and river and in the depths of the northern forest.

He first thought of Isle Ste Marie (Manitoulin Island) as the safest place for the headquarters of a new mission, but finally decided to go to Isle St Joseph (Christian Island), just off Huronia to the north. There, on the bay that indents the south-east corner of the island, he directed that land should be cleared for the building. The work of evacuating Ste Marie began early in May, and on the 15th of the month the buildings were set on fire. The valuables of the mission were placed in a large boat and on rafts; and, with heavy hearts, the fathers and their helpers went aboard for the journey to their new home twenty miles away.

The new Ste Marie which the Jesuits built on Isle St Joseph was in the nature of a strong fort. Its walls were of stone and cement, fourteen feet high and loopholed. At each corner there was a protecting bastion, and the entire structure was surrounded by a deep moat. It was practically impregnable against Indian attack, for it could not be undermined, set on fire, or taken by assault. A handful of men could hold it against a host of Iroquois.

About the sheltering walls of Ste Marie the Indians gathered, to the number of seven or eight thousand by the autumn of 1649. Here the missionaries continued the good work. The only outposts now were among the Algonquins along the shore of Georgian Bay, and the Petun missions of St Mathias, St Matthieu, and St Jean. But the Petuns were presently to share the fate of the Hurons; and Garnier and Chabanel, who were stationed at St Jean, were to perish as had Daniel, Brebeuf, and Lalemant.

During the autumn Ragueneau learned that a large body of Iroquois were working their way westward towards St Jean. He sent runners to the threatened town, and ordered Chabanel to return to Ste Marie and warned Garnier to be on his guard. On the 5th of December Chabanel set out for Ste Marie with some Petun Hurons, and Garnier was left alone at St Jean. Two days later, while the warriors were out searching for their elusive foes, a band of Senecas and Mohawks swept upon the town, broke through the defences, and proceeded to butcher the inhabitants. Garnier fell with his flock. In the thick of the slaughter, while baptizing and absolving the dying, he was smitten down with three bullet wounds and his cassock torn from his body. As he lay in agony the moans of a wounded Petun near by drew his attention. Though spent with loss of blood, though his brain reeled with the weakness of approaching death, he dragged himself to his wounded red brother, gave him absolution, and then fell to the ground in a faint. On recovering from his swoon he saw another dying convert near by and strove to reach his side, but an Iroquois rushed upon him and ended his life with a tomahawk.

In a sense Chabanel was less fortunate than Garnier. On the day following the massacre of St Jean he was hastening along the well-beaten trail towards Ste Marie, when the sound of Iroquois war-cries in the distance alarmed his guides, and all deserted him save one. This one did worse, for he slew the priest and cast his body into the Nottawasaga river. This murderer, an apostate Huron, afterwards confessed the crime, declaring that he had committed it because nothing but misfortune had befallen him ever since he and his family had embraced Christianity.

For some months after the death of Garnier and Chabanel the Jesuits maintained the mission of St Mathias among the Petuns in the Blue Hills. Here Father Adrien Greslon laboured until January 1650, and Father Leonard Garreau until the following spring. Garreau was then recalled, leaving not a missionary on the mainland in the Huron or the Petun country.