Similar arguments have been used by the opponents of the germ theory of epidemic disease, and both parties have triumphantly challenged an appeal to the microscope and the chemist’s balance to decide the question. Without committing myself in the least to De la Rive’s notion, without offering any objection here to the doctrine of spontaneous generation, without expressing any adherence to the germ theory of disease, I would simply draw attention to the fact that in the atmosphere we have particles which defy both the microscope and the balance, which do not darken the air, and which exist, nevertheless, in multitudes sufficient to reduce to insignificance the Israelitish hyperbole regarding the sands upon the seashore.

The varying judgments of men on these and other questions may perhaps be, to some extent, accounted for by that doctrine of relativity which plays so important a part in philosophy. This doctrine affirms that the impressions made upon us by any circumstance, or combination of circumstances, depends upon our previous state. Two travelers upon the same peak, the one having ascended to it from the plain, the other having descended to it from a higher elevation, will be differently affected by the scene around them. To the one nature is expanding, to the other it is contracting, and feelings are sure to differ which have two such different antecedent states.

In our scientific judgments the law of relativity may also play an important part. To two men, one educated in the school of the senses, who has mainly occupied himself with observation, and the other educated in the school of imagination as well, and exercised in the conception of atoms and molecules to which we have so frequently referred, a bit of matter, say 1/50000 of an inch in diameter, will present itself differently. The one descends to it from his molar hights, the other climbs to it from his molecular lowlands. To the one it appears small, to the other large. So also as regards the appreciation of the most minute forms of life revealed by the microscope. To one of these men they naturally appear conterminous with the ultimate particles of matter, and he readily figures the molecules from which they directly spring; with him there is but a step from the atom to the organism. The other discerns numberless organic gradations between both. Compared with his atoms, the smallest vibrios and bacteria of the microscopic field are as behemoth and leviathan.

The law of relativity may to some extent explain the different attitudes of these two men with regard to the question of spontaneous generation. An amount of evidence which satisfies the one entirely fails to satisfy the other; and while to the one the last bold defense and startling expansion of the doctrine will appear perfectly conclusive, to the other it will present itself as imposing a profitless labor of demolition on subsequent investigators. The proper and possible attitude of these two men is that each of them should work as if it were his aim and object to establish the view entertained by the other.

I trust, Mr. President, that you—whom untoward circumstances have made a biologist, but who still keep alive your sympathy with that class of inquiries which nature intended you to pursue and adorn—will excuse me to your brethren if I say that some of them seem to form an inadequate estimate of the distance which separates the microscopic from the molecular limit, and that, as a consequence, they sometimes employ a phraseology which is calculated to mislead.

When, for example, the contents of a cell are described as perfectly homogeneous, as absolutely structureless, because the microscope fails to distinguish any structure, then I think the microscope begins to play a mischievous part. A little consideration will make it plain to all of you that the microscope can have no voice in the real question of germ structure. Distilled water is more perfectly homogeneous than the contents of any possible organic germ. What causes the liquid to cease contracting at 39° F., and to grow bigger until it freezes? It is a structural process of which the microscope can take no note, nor is it likely to do so by any conceivable extension of its powers. Place this distilled water in the field of an electro-magnet, and bring a microscope to bear upon it. Will any change be observed when the magnet is excited? Absolutely none; and still profound and complex changes have occurred.

First of all, the particles of water are rendered diamagnetically polar; and secondly, in virtue of the structure impressed upon it by the magnetic strain of its molecules, the liquid twists a ray of light in a fashion perfectly determinate both as to quantity and direction. It would be immensely interesting to both you and me if one here present, who has brought his brilliant imagination to bear upon this subject, could make us see as he sees the entangled molecular processes involved in the rotation of the plane of polarization by magnetic force. While dealing with this question he lived in a world of matter and of motion to which the microscope has no passport, and in which it can offer no aid. The cases in which similar conditions hold are simply numberless. Have the diamond, the amethyst, and the countless other crystals formed in the laboratories of nature and of man, no structure? Assuredly they have, but what can the microscope make of it? Nothing. It cannot be too distinctly borne in mind that between the microscopic limit and the true molecular limit there is room for infinite permutations and combinations. It is in this region that the poles of the atoms are arranged, that tendency is given to their powers, so that when these poles and powers have free action and proper stimulus in a suitable environment, they determine first the germ and afterwards the complete organism. This first marshaling of the atoms on which all subsequent action depends baffles a keener power than that of the microscope. Through pure excess of complexity, and long before observation can have any voice in the matter, the most highly trained intellect, the most refined and disciplined imagination, retires in bewilderment from the contemplation of the problem. We are struck dumb by an astonishment which no microscope can relieve, doubting not only the power of our instrument, but even whether we ourselves possess the intellectual elements which will ever enable us to grapple with the ultimate structural energies of nature.

But the speculative faculty, of which imagination forms so large a part, will nevertheless wander into regions where the hope of certainty would seem to be entirely shut out. We think that though the detailed analysis may be, and may ever remain, beyond us, general notions may be attainable. At all events, it is plain that beyond the present outposts of microscopic inquiry lies an immense field for the exercise of the imagination. It is only, however, the privileged spirits who know how to use their liberty without abusing it, who are able to surround imagination by the firm frontiers of reason, that are likely to work with any profit here. But freedom to them is of such paramount importance that, for the sake of securing it, a good deal of wildness on the part of weaker brethren may be overlooked. In more senses than one Mr. Darwin has drawn heavily upon the scientific tolerance of his age. He has drawn heavily upon time in his development of species, and he has drawn adventurously upon matter in his theory of pan-genesis. According to this theory, a germ already microscopic is a world of minor germs. Not only is the organism as a whole wrapped up in the germ, but every organ of the organism has there its special seed.

This, I say, is an adventurous draft on the power of matter to divide itself and distribute its forces. But, unless we are perfectly sure that he is overstepping the bounds of reason, that he is unwittingly sinning against observed fact or demonstrated law—for a mind like that of Darwin can never sin wittingly against either fact or law—we ought, I think, to be cautious in limiting his intellectual horizon. If there be the least doubt in the matter, it ought to be given in favor of the freedom of such a mind. To it a vast possibility is in itself a dynamic power, though the possibility may never be drawn upon.

It gives me pleasure to think that the facts and reasonings of this discourse tend rather towards the justification of Mr. Darwin than towards his condemnation, that they tend rather to augment than to diminish the cubic space demanded by this soaring speculator; for they seem to show the perfect competence of matter and force, as regards divisibility and distribution, to bear the heaviest strain that he has hitherto imposed upon them.