The internal administration of arsenic often yields excellent results in chronic eczema. Dissolve 1 dram of arsenic and 1 dram of carbonate of potassium in 1 pint of boiling water, and give 1 ounce of this twice a day in water, after feeding. An alkali internally may be of service. As such, one may give 2 ounces of bicarbonate of soda twice daily. Sublimed sulphur may also be tried in ounce doses twice daily.

PUSTULES (IMPETIGO).

Impetigo is an inflammatory disease of the skin, characterized by the formation of distinct pustules, about the size of a pea or a bean, without itching. The pustules develop from the papular layer of the skin, and contain a yellowish-white pus. After reaching maturity they remain stationary for a few days, then they disappear by absorption and dry up into crusts, which later drop off, leaving upon the skin a red spot that soon disappears. Occasionally the crusts remain firmly adherent for a long time, or they may be raised and loosened by the formation of matter underneath. The dry crusts usually have a brown or black appearance.

Causes.—Impetigo affects sucking calves, in which the disease appears upon the lips, nostrils, and face. It is attributed to some irritant substance contained in the mother's milk. Impetigo is also witnessed among grazing animals, regardless of age, and it especially attacks animals with white hair and skin. The mouth, face, and limbs become covered with pustules, which may rupture in a few hours, followed by rapid and successive incrustations; the scabs frequently coalesce, covering a large surface; pus may form under them, and thus the whole thickness of the skin become involved in the morbid process. This form of the disease is attributed to the local irritant properties of such plants in the pasture as St. John's wort (Hypericum perforatum), smartweed (Polygonum hydropiper), vetches, honeydew, etc. Buckwheat, at the time the seeds become ripe, is said to have caused it; also bedding with buckwheat straw.

Treatment.—Sucking calves should be removed from the mother, and a purgative given to the latter to divert the poisonous substance secreted with the milk. When the more formidable disease among grazing cattle appears, the pasturage should be changed and the affected parts of the animal thoroughly anointed once a day with sweet oil containing 2 drams of carbolic acid to the pint. This should be continued until the crusts soften and begin to drop off, then the parts may be cleansed thoroughly with warm water and soap. Subsequently the white precipitate ointment or carbolized cosmoline should be applied daily until the parts are healed.

PEMPHIGUS (WATER BLISTERS).

This is an inflammatory disease of the skin, characterized by successive formations of rounded, irregularly shaped water blisters, varying in size from a pea to a hen's egg.

Causes.—Obscure.

Symptoms.—The formation of a blister is preceded by a congestion or swelling of the skin. Yellowish-colored water collects beneath the cuticle, which raises the latter from its bed in the form of a blister. The blisters appear in a succession of crops; as soon as one crop disappears another forms. They usually occur in clusters, each one being distinct, or they may coalesce. Each crop usually runs its course in a week. The disease is attended with itching or burning sensations which cause the animal to rub, thereby frequently producing excoriations and formation of crust on the affected region.

Treatment.—Give a tablespoonful of the following-described mixture in feed twice a day: Saltpeter, cream of tartar, and sulphur, equal parts by weight. The blisters should be opened as soon as formed, to allow the escape of the serum, followed by a wash composed of chlorid of zinc, 1 dram to 15 ounces of water. When there is any formation of crusts, carbolized cosmoline should be applied.