During the course of infectious diseases secondary diseases or complications may arise which are largely caused by bacteria other than those producing the original malady. These complications are often so severe as to become fatal. In general it may be stated that they are due to filthy surroundings, and hence cleanliness may become an important aid to recovery.

The treatment of infectious diseases is given under each malady so far as this is allowable or advisable. These diseases are not, as a rule, amenable to treatment. When the symptoms have once appeared the disease is liable to run its course in spite of treatment, and if it is one from which animals usually recover, all that can be done is to put them into the most favorable surroundings. Many infectious diseases lead sooner or later to death, treatment is useless so far as the sick are concerned, and it may be worse than useless for those not yet infected. All animals suffering with infectious diseases are more or less directly a menace to all others. They represent for the time being manufactories of disease germs, and they are giving them off more or less abundantly during the period of disease. They may infect others directly or they may scatter the virus about, and the surroundings may become a future source of infection for healthy animals. This leads us to the subject of prevention as the most important of all which claim our attention. In this place only a few general remarks will suffice to bring the subject before the reader.

The most important thing is to keep disease away from a herd or farm. To do this all sick or suspicious animals should be avoided. A grave form of disease may be introduced by apparently mild or trivial cases brought in from without. It is generally conceded that continual change and movement of animals are the most potent means by which infectious diseases are disseminated.

With some cattle diseases, such as anthrax, rinderpest, and pleuropneumonia, preventive inoculation is resorted to in some countries. This may be desirable when certain diseases have become established in any locality so that eradication is impossible. It should not be practiced in territories where a given disease may still be extirpated by ordinary precautions. Preventive inoculation is applicable to only a few maladies, and therefore its aid in the control of diseases is limited.

When an infectious disease has gained foothold in a herd the course to be pursued will depend upon the nature of the malady. A good rule is to kill diseased animals, especially when the disease is liable to run a chronic course, as in tuberculosis. The next important step is to separate the well from the sick by placing the former on fresh ground. This is rarely possible; hence the destruction or removal of the sick, with thorough disinfection of the infected locality, is the next thing to be done. As to the disinfectants to be used, special directions are given under the various diseases, to which the reader is referred. Here we will simply call attention briefly to the general subject.

DISINFECTION AND DISINFECTANTS.

Disinfection consists in the use of certain substances which possess the power to destroy bacteria or their spores, or both. Those which are cheapest and most available for animal diseases are ordinary freshly slaked lime or unslaked in powder, chlorid of lime, crude carbolic acid, corrosive sublimate, formaldehyde gas, formalin, and compound cresol solution.

(1) Slaked lime is perhaps the most easily procured, but its disinfecting power is limited. While it is capable of destroying all bacteria in their vegetative state, it is unable to destroy such spores as those of anthrax and blackleg. It is probable, however, that in incrusting spores it may destroy their vitality sooner or later. It is regarded as safe practice to use only spore-destroying substances for the virus of those diseases of which we have no definite knowledge. Nevertheless, in the absence of other disinfectants, lime is very useful. It may be employed as a whitewash on wood and stone and sprinkled as a dilute wash or in powder over yards, manure heaps, and over carcasses before they are buried, and over the ground on which they have lain to prevent other animals from carrying the infection away.

(2) Chlorid of lime is more efficient than simple slaked or unslaked lime, as it destroys spores. It is the ordinary bleaching powder of commerce and is quite unstable, hence old preparations, unless sealed, are of little value. A 5 per cent solution is sufficiently strong for all spore-bearing bacteria (3 ounces in 2 quarts of water). It may be efficiently applied to the walls and floor of an infected stable by mixing with limewash in the proportion of 6 ounces of the lime to each gallon of limewash. The ceilings and those portions of the walls which can not be reached should be disinfected by means of chlorin gas liberated from the chlorid of lime by crude carbolic acid. This is accomplished by making a cone of 5 or 6 pounds of chlorid of lime, in the top of which a deep crater is made for the placement of from 1 to 2 pints of crude acid. The edge of the crater is thereupon pushed into the fluid, when a lively reaction follows. The fumes of chlorin are strongly irritating to the respiratory tract and therefore all live stock should be removed before the work is started. Owing to the heat generated, it is advisable to place the lime in an iron crucible and to have nothing inflammable within a radius of 2 feet. The number and location of these cones of chlorid of lime depend on the size and structure of the building to be disinfected. As a rule, it may be stated that chlorin gas liberated from the above-sized cone will be sufficient for disinfecting 5,200 cubic feet of air space.

(3) Crude carbolic acid. The ordinary purified carbolic acid is too expensive to be used on a large scale, and the crude produce is a very good substitute. This is made more powerful by mixing with it an equal volume of commercial sulphuric acid. While the sulphuric acid is being added to the crude carbolic acid much heat is evolved, and if the glass jar in which the two are mixed is placed in cold water the resulting product is said to have a higher disinfecting power. The mixture is added to water enough to make a 5 per cent solution (about 7 ounces to 4 quarts of water). This is strong enough for all purposes. It may be kept in wood or glass, but not in metal, owing to the corroding action of the acid. It should be used freely on woodwork and on infected floors, and a force pump of the kind used by orchardists is very convenient as a means of applying the disinfectant. If the solution is warm when applied, it will penetrate the woodwork better than when cold, especially if the spraying is done during cold weather. The addition of air-slaked lime in any quantity that will dissolve in water to the above solution (say 1½ pounds of lime to 7 ounces of crude carbolic acid to each gallon of water) is preferred by many, as it makes any neglected places at once visible and leaves cleaner and better air within the buildings. In most cases in which its application becomes desirable—and this rule should apply to all disinfections—the disinfected stables, stalls, etc., should remain vacant as long as possible before cattle are again stabled therein.