199 Op. cit., p. 420.
200 Rev. mens. de Méd. et de Chir., Paris, Feb., 1878.
201 Ibid.
202 Med. Times and Gaz., Lond., 1862, vol. i. p. 403.
203 Ibid., Dec., 1863.
The kidneys are not infrequently involved in inherited syphilis. Parrot reports the pathological change to consist of a proliferation of small round cells in the intertubular connective tissue, followed by contraction, obliteration of the tubules, and degeneration of their epithelium.
Bradley has reported204 the case of a child aged four months in whom a well-marked syphilitic eruption and an attack of acute Bright's disease were coincident. Mercurial treatment for three weeks cured both.
204 British Med. Journ., Feb. 4, 1876.
Coupland has reported two cases of parenchymatous nephritis associated with inherited syphilis, but advances no proof that it was not an accident. Gummata have been from time to time found in the kidneys of very young children who have died from their effects and from other visceral lesions due to syphilis.205 Cases of enlargement, of fibroid, fatty, and gelatinous degenerations of the suprarenal capsules, have been recorded.
205 See discussion in Clinical Soc. of London, Jan., 1880; "Remarks on Visceral, and especially on Renal, Syphilis," by Barthelémy, Annales de Derm. et Syph., April, 1881.