Hutchinson: Trans. State Med. Society of New York, 1877, p. 208.

Otto: Medical Repository, 1803, vol. vi.; 3 F., 8 cases.

Pepper: Philada. Med. Times, 1881, vol. xii. p. 109; 1 case—Lancaster county family described by Dunn.

Sewell: Med. Chronicle, Montreal, 1857, vol. iv.; 2 F., 4 or 5 cases.

Smith: Philadelphia Medical Museum, 1801, vol. i. p. 284.

Traneus: St. Louis Med. and Surgical Journal, 1870, p. 535; 1 F., 4 cases.

Townsend: Boston Med. and Surgical Journal, vol. lv. p. 447; 1 F., 3 cases.


ADDISON'S DISEASE.

DEFINITION.—A constitutional affection characterized by asthenia without emaciation, a depressed circulation, gastric irritability, and usually pigmentation of the skin. In the majority of cases it is associated with a fibro-caseous degeneration of the suprarenal capsules, and in many there are changes in the abdominal sympathetic system.