194 Can. Med. Assoc. Trans., vol. i., 1877.
195 Phila. Med. Times, 1885.
That other alterations may occur in cases of Addison's disease appears well established, though some still regard the caseo-fibrous change essential and specific. Atrophy of one or both glands has been frequently seen. Jaccoud gives 7 cases in his tables. Good recent cases have been described by W. B. Hadden,196 Hebb,197 and Goodhart.198 The atrophy is due to a chronic interstitial process similar to cirrhosis of the liver. Hadden199 states that the lesion is identical with that in the thyroid gland in myxoedema.
196 British Medical Journal, 1885.
197 Lancet, 1883, i.
198 Path. Soc. Trans., 1882.
199 Loc. cit.
Absence of one or both the capsules has been noted by Legg, Spender, Borland200 and Hubbard.201
200 Boston Med. and Surg. Journal, 1867.
201 Proceedings of Conn. Med. Society, 1868–71.