TREATMENT.—As food, iron, and tonics have little or no effect upon the disease after it has passed through its incipient stages, therapeutic resources are limited. The evacuation of the uterine cavity, as shown by Graefe's cases, exercises a favorable influence upon the course of the affection. Gusserow advises the artificial interruption of pregnancy whenever grave symptoms occur, and the weight of professional opinion is very decidedly in favor of such a course. Negative results have attended all efforts at transfusion.

HÆMOPHILIA.

Kehrer4 has recently called attention to the apparent influence of pregnancy in the development of the hemorrhagic diathesis. This influence, however, is seldom observed, and then only in cases of distinct, individual predisposition.

4 Arch. f. Gyn., x. p. 201.

TREATMENT.—The induction of premature labor, or, at times, of abortion, is indicated.

PLETHORA.

The experiments and observations of Spiegelberg5 and Gscheidlen prove the possibility of the occurrence of plethora during gestation. Actual increase of the red corpuscles, albumen, and iron in the blood is observed during the second half of pregnancy, and then only under the most favorable conditions. As described by Spiegelberg, the symptoms are—mammary and cerebral congestions, palpitation, vertigo, constipation, hepatic torpor.

5 Lehrbuch d. Geburtshülfe, Lahr, 1882, p. 58.

TREATMENT.—Restricted diet, muscular exercise, and an occasional saline purge will relieve the troublesome symptoms. Spiegelberg is convinced of the value of bleeding in selected cases.

Circulatory Disturbances.