Klebs18 is of the opinion that, although the so-called chronic uterine infarct may be of inflammatory origin, in the majority of cases the clinical and anatomical demonstration is lacking. With Scanzoni and Virchow, he distinguishes two forms of the disease, the one consisting in hyperplasia of the muscular elements, the other in a similar change in the connective tissue.
18 Handbuch der Pathologischen Anatomie, Berlin, 1873, iv. p. 878.
Birch-Hirschfeld19 supports the doctrine of Scanzoni, that the stage of induration at least is of an inflammatory nature. The connective tissue is formed out of emigrated white blood-corpuscles. Hypertrophy of the muscular elements is also observed in certain cases.
19 Pathologische Anatomie, p. 1131.
Fritsch20 has materially strengthened the position of Scanzoni by his recent anatomical investigations. Mayrhofer21 substantially reproduces Scanzoni's doctrines.
20 Op. cit., p. 309 et seq., Stuttgart, 1885.
21 Entwicklungsfehler und Entzündungen des Uterus.
Finally, the great majority of modern clinicians have accepted Scanzoni's teachings as originally uttered or as modified in non-essential details. Schroeder,22 De Sinéty,23 and A. Martin24 are notable examples of the truth of this statement.
22 Carl Schroeder, Handbuch der Krankheiten d. Weibl. Geschlechtsorgane, Leipzig, 1881, p. 91.
23 L. de Sinéty, Manuel practique de Gynécologie et des Maladies des Femmes, Paris, 1879.