5 Doctrina de Morbis Venereis, Vienna.

6 Arch. f. Ophthalm., Bd. i. Erst Abth.

7 Virchow's Archiv, Bd. lxxxiv. 269.

8 Wien. Med. Wochenschrift, xxxi. 1881, 17.

9 Lond. Patholog. Soc. Trans., 1877.

10 The Brain and its Diseases, vol. i. p. 76.

11 Archiv. de Physiologie, 1871-72, p. 319; also to his “Leçons sur le Syphilis hered.,” Progrès méd., 1877 and 1878.

12 Arch. de Tocologie, x. 411.

Recorded cases prove decisively that even after puberty specific nervous affections may primarily attack the unfortunate offspring. Thus, Nettleship reports13 the development of a cerebral gumma in a girl of ten years, and J. A.. Ormerod14 of a tumor of the median nerve (probably gummatous) in a woman of twenty-three, both the subjects of inherited syphilis. Thomas S. Dowse15 details a case of cerebral gumma at the age of ten years, and Samuel Wilks16 one of epilepsy, from inherited taint, in a boy of fourteen. J. Hughlings-Jackson reports17 paraplegia with epilepsy in a boy of eight, hemiplegia in a girl of eighteen, and hemiplegia in a woman of twenty-two;18 the nervous affection in each case being associated with or dependent upon inherited syphilis. E. Mendel reports19 a case of a child who had inherited syphilis, and developed in her fifteenth year a maniacal attack with hallucinations. I have seen cerebral syphilis occur at twenty-one years of age as the first evident outbreak of the inherited disorder.

13 Trans. Lond. Path. Soc., xxxii. 13.