Have so incensed that I am reckless what

I do to spite the world.

Macbeth. Act iii. Sc. 1.

So weary with disasters, tugg'd with fortune,

That I would set my life on any chance,

To mend it, or be rid on 't.

Macbeth. Act iii. Sc. 1.

Things without all remedy

Should be without regard; what 's done is done.

Macbeth. Act iii. Sc. 2.