Lozana in his History mentions a revolution in Paraguay in 1555, which was headed by an Irishman named Nicholas Colman. This revolution was quickly suppressed by the Spanish viceroy, Yrala, but Colman led a second revolution in 1570, when Captain Rigueline was governor of Guayra. The mutineers named Colman for their chief, put their treasures into canoes, and floated down the Parana until their boats were capsized by some rapids, probably the falls of Apipe in Misiones. The viceroy, on hearing of the revolt, sent troops to bring back the fugitives, and the latter were treated with unusual clemency. Lozana describes Colman as a daring, turbulent buccaneer. For fifteen years he seems to have played an important part in Guayra; his subsequent fate is unknown.
In 1626 an expedition commanded by James Purcell, an Irishman, established itself on the island of Tocujos, in the mouth of the Amazon.
Captain Charles O'Hara was sent by Governor Arana from Montevideo in March, 1761, to destroy the old landmarks of Rio Negro and Ching between the dominions of Portugal and Spain. The officer next under him was Lieutenant Charles Murphy, afterwards governor of Paraguay. This expedition suffered great hardships.
Several of the expeditions of the privateers of the eighteenth century sailed from Ireland. Dampier, a skilful navigator, went on a cruise to intercept the Spanish galleons returning from the River Plate with booty supposed to be worth £600,000 sterling. He sailed from Kinsale in September, 1703, with two vessels, and no doubt amongst the crews were many Irishmen. It was on this expedition that Alexander Selkirk, a Scotch sailor, was put on shore at Juan Fernandez in 1704, where he remained until rescued by Captain Rogers, who commanded the Duke, a vessel of 320 tons, which sailed from Cork on September 1, 1708, touched by chance at Juan Fernandez, and found the original of Defoe's remarkable story, Robinson Crusoe, who presented a wild appearance dressed in his goatskins.
In 1765 Captain Macnamara, with two vessels called the Lord Clive and the Ambuscade, mounting between them 104 guns, attempted to take Colonia, in front of Buenos Ayres, from the Spaniards. Having shelled the place for four hours, Macnamara expected every moment to see a white flag hoisted, when, by some mishap, the Lord Clive took fire, and 262 persons perished. The Spaniards fired upon the poor fellows in the water, only 78 escaping to land. Macnamara was seen to sink. His sword was found a few years ago by a Colonia fisherman, who presented it to the British consul at Montevideo. Most of the Irish names still extant in the Argentine provinces, such as Sarsfield, Carrol, and Butler, are probably derived from these captives. Among the descendants of the survivors of Macnamara's expedition may be mentioned the ablest lawyer ever known in Buenos Ayres and for many years Prime Minister, the late Dr. Velez Sarsfield, and also Governor O'Neill.
The year 1586 saw an expedition of a very different character, consisting of the first Jesuits sent to convert Paraguay, under the direction of Father Thomas Field, an Irishman, and son of a Limerick doctor. Their vessel fell into the hands of English privateers off the Brazilian coast, but the sea rovers respected their captives, and after sundry adventures the latter landed at Buenos Ayres, whence they proceeded over land to Cordoba. The year following they set out for Paraguay, where Father Field and his companions laid the foundation of the Jesuit commonwealth of Misiones, which had such wonderful development in the following two centuries as to cause Voltaire to admit that "the Jesuit establishment in Paraguay seems to be the triumph of humanity."
Another Irish Jesuit, Father Thaddeus Ennis, appears in authority in Misiones shortly before the downfall. In 1756, when Spain ceded San Miguel and other missions to Portugal, Father Ennis was entrusted with the removal lower down to Parana of such tribes as refused to become Portuguese subjects.
Yet another Jesuit, Father Falkiner, son of an Irish Protestant doctor in Manchester, who had himself studied medicine, was one of the most successful travellers and missionaries of the 18th century. Among his friends in London was a ship-captain who traded from the coast of Guinea to Brazil, carrying slaves for the company recently established by Queen Anne's patent, and he it doubtless was who prevailed on the young physician to try a seafaring life. In one of his voyages as ship surgeon, from Guinea to Buenos Ayres, he fell ill at the latter port, and, there being no hotels, he had the good fortune to enjoy the hospitality of the Jesuit superior, Father Mahony, whose name proclaims his Irish nationality. Such was the impression made on Falkiner by the kindness of the Jesuits that he shortly afterwards was received into the Church and entered as a novice in the College of St. Ignatius at Buenos Ayres. He spent the first years of his missionary career in Misiones and Tucuman. Later on he was despatched by his superior to Patagonia, and his success there during 27 years was almost equal to what has already been mentioned of Father Field in Paraguay. He converted many tribes, and traversed nearly every part of Patagonia from Rio Negro to Magellan's Straits, and as far inland as the Andes. He knew most of the Indian tongues, and by his winning manners and knowledge of medicine gained a great influence over the savages. When he published his life and travels, such was the effect of his book upon the king of Spain that he at once ordered surveys and settlements to be made along the Patagonian coast, which Father Falkiner represented as exposed to seizure by the first adventurer who should land there. Father Falkiner's book has been translated into French, German, and Spanish. He returned to England and died at Spetchly, Worcestershire, near the end of the 18th century.
In 1774 the bishop of Ayachucho was Dr. James O'Phelan, who rebuilt the old Cathedral of Pasco. His father was an Irish officer in the Spanish army.