First known printing in America; done in Mexico. See "Origin and Progress of Printing," viii, 1.

1541. Charles V heads an unsuccessful expedition against Algiers.

Hungary overrun by the Turks, under Solyman the Magnificent.

King John III of Portugal requests Francis Xavier and other Jesuits to undertake missions to his colonies.

De Soto reaches the Mississippi River. See "De Soto Discovers the Mississippi," ix, 277.

1542. Discovery of Japan by the Portuguese.*

Execution of Catherine Howard, fifth queen-consort of Henry VIII. He assumes the title of king of Ireland.

Battle of Solway Moss; successful invasion of Scotland by the English.

War renewed between Francis I and Charles V.

Trade with Japan by the Portuguese permitted.