Pickett says that in 1728 the colony of Louisiana, which at that date occupied nearly all the southwest part of the United States, including Louisiana, Mississippi, and Alabama, was in a flourishing condition, its fields being cultivated, by more than two thousand slaves, in cotton, indigo, tobacco, and grain.

Peter Purry, the founder of Purryville, in South Carolina, in his description of the Province of South Carolina, drawn up in Charleston in 1731, says, "Flax and cotton thrive admirably."

In 1734 cotton-seed was planted in Georgia, being sent there by Philip Nutter, of Chelsea, England. Francis Moore, who visited Savannah in 1735, in his description of that place, says: "At the bottom of the hill, well sheltered from the north wind and in the warmest part of the garden, there was a collection of West Indian plants and trees, some coffee, some cocoa-nuts, cotton, etc."

About the same time the settlers on the Savannah River, about twenty-one miles north of Savannah, are said to have experimented with cotton, the date being fixed by McCall as 1738. One of the striking features connected with the early culture of cotton in the American colonies is that it was grown as far north as the 39° of latitude. Trench Coxe, of Philadelphia, who contributed so greatly to the early success of the culture and manufacture of cotton in the United States, says: "It is a fact well authenticated to the writer that the cultivation of cotton on the garden scale, though not at all as a planter's crop, was intimately known and thoroughly practised in the vicinity of Easton, in the county of Talbot, on the eastern shore of the Chesapeake Bay, Maryland, as early as 1736."

Its cultivation was so well understood in this part of the country that, according to the same authority, the necessities of the Revolutionary War occasioned it to be raised for army use in the counties of Cape May, New Jersey, and Sussex, Delaware, and it continued to be raised, though only in small quantities, for family use. At the time of the Revolution, the home-grown cotton was sufficiently abundant in Pennsylvania to supply the domestic needs of that State. Cotton was also cultivated in Charles, St. Mary's, and Dorchester counties, Maryland, as late as 1826. And at a later date (1861-1864) upland cotton was cultivated, and at the prices current at that date was a most profitable crop on the eastern shore of Maryland. Cotton was grown with very good results in Northampton County, on the eastern shore of Virginia, in those years.

The culture and improvement of cotton had received considerable attention by the planters of South Carolina and Georgia as early as 1742. In 1739 Samuel Auspourguer attested under oath that the "climate and soil of Georgia are very fit for raising cotton." William Spicer also certified to the adaptability of the country for cotton production, and that he had "brought over with him (to London) several pods of cotton which grew in Georgia."

A tract entitled A State of the Province of Georgia, Attested Under Oath in the Court of Savannah, published in 1740, says of cotton that "large quantities had been raised, and it is much planted; but the cotton, which in some parts is perennial, dies here in the winter; nevertheless the annual is not inferior to it in goodness, but requires more trouble in cleansing from the seed." In the same tract it was "proposed that a bounty be settled on every product of the land, viz., corn, peas, potatoes, wine, silk, cotton," etc. In A Description of Georgia, by a Gentleman who has Resided there Upward of Seven Years and was One of the First Settlers, published in London in 1741, the author states that "the annual cotton grows well there, and has been by some industrious people made into clothes."

Samuel Seabrook, in An Important Inquiry into the State and Utility of Georgia, published in 1741, says, "Among other beneficial articles of trade which it is found can be raised there, cotton, of which some has also been brought over as a sample, is mentioned." In his description of St. Simon's Island the same author says: "The country is well cultivated, several parcels of land not far distant from the camp of General Oglethorpe's regiment having been granted in small lots to the soldiers, many of whom are married. The soldiers raise cotton, and their wives spin it and knit it into stockings."

A publication in London in 1762 says: "What cotton and silk both the Carolinas send us is excellent and calls aloud for encouragement of its cultivation in a place well adapted to raise both."

Captain Robinson, an Englishman who visited the coast of Florida in 1754, says the "cotton-tree was growing in that country." The Florida territory then extended from the Atlantic to the Mississippi River. That it was cultivated in East Florida about ten years after this is evidenced by William Stork, who says, "I am informed of a gentleman living upon the St. John's that the lands on that river below Piccolata are in general good, and that there is growing there now (1765) good wheat, Indian corn, indigo, and cotton."