260 Sea-fight off Mylæ. Carthaginians defeated by Romans.
256 Sea-fight off Ecnomus. Carthaginian fleet defeated. Romans invade Africa.
255 Carthaginians under Xanthippus defeat the Romans under Regulus. Loss of Roman fleet on homeward voyage.
254 Roman victory at Panormus.
253 Roman fleet destroyed in a storm.
249 Battle of Drepanum. Carthaginian victory.
248-243 Success of Carthaginians under Hamilcar Barca on Italian coast and in Sicily.
242 Battle off Ægates islands. Romans under Catulus defeat Carthaginian fleet.
241 Hamilcar Barca makes peace, agreeing to evacuate Sicily and to pay indemnity. Sicily lost to the Carthaginians.