Cyrnus came under Etruscan influence after the withdrawal of the Phocæans. The Etruscans, it appears, had already taken possession of the fertile plain on the lower Vulturnus and had established there a number of settlements, whose centre was at Capua. They now proceeded to attack Hellenic Cumæ (presumably in 524). Here, however, the superior military skill of the Greeks won the victory, and the latter were able to defend the Latin cities, which were friendly to them, from being brought into subjection by the Etruscans. The strength of Cumæ, however, was not sufficient to keep up the unequal fight for long and it was due only to the intervention of the Syracusans that Hellenism maintained itself here until the end of the fifth century.
Nearly contemporaneously with the beginnings of colonisation in the west the Hellenes began to spread toward the north and southeast. The Chalcidians again took the first place. Opposite Eubœa a long peninsula projects from the north into the Ægean Sea, which, on account of the numerous indentations of its coast, as well as the fertility of its soil, invited settlement. A long succession of Grecian colonial towns grew up here, the most of which were founded from Chalcis; hence the name Chalcidice, which the peninsula bore in later times. The Corinthians followed the Chalcidians here, just as they had done in the west. On the narrow isthmus joining the peninsula of Pallene with the main body of Chalcidice they founded the colony of Potidæa (in 600) which remained the most important city of this region until the time of the Peloponnesian War. The original Thracian population maintained itself only on the rugged slopes of Athos.
Further east, in the first half of the seventh century, the Parians took possession of the mountainous island of Thasos, which at that time was still covered with a thick primeval forest. The new settlers soon crossed over to the near-lying mainland, where they established a number of commercial stations, as Œsyma and Galepsus, which had to maintain themselves through long struggles with the warlike Thracian tribes. Opposite Thasos, on the fruitful plain between Nestus and Lake Bistonis, the Clazomenæans founded Abdera in 651, but they could not long maintain themselves against the attacks of the Thracians. Colonists from Teos, who emigrated after the conquest of Ionia by the Persians (545) and took possession of the deserted place, were more successful; Abdera now became the most important city on this whole coast and also took an active part in the intellectual life of the nation.
Lesbos and Tenedos were for a long time the most advanced posts of the Hellenic world toward the northeast. Not until the eighth century do the inhabitants of these islands appear to have succeeded in taking possession of the south of Troas, from the wooded slopes of Ida to the entrance to the Hellespont. None of the numerous settlements founded here, however, became very important. The Lesbians then went further and crossed over to the European shore of the Hellespont, where they built Sestus at the narrowest point of the strait and Alopeconnesus on the northern coast of the Thracian Chersonesus. Ænus, at the mouth of the mighty Hebrus, the principal river of Thrace, was also colonised by Mytileneans. The further expansion of the Greeks on this coast was arrested by the warlike tribes of Thrace.
The Lesbians were soon followed by the Milesians. In 670 they established Abydos, opposite Sestus, and at about the same time (675) founded Cyzicus on the isthmus connecting the mountainous peninsula of Arcotonnesus with the Asiatic mainland. Other Ionian cities also took part in the colonisation of these regions. Lampsacus was colonised from Phocæa (651); Elæus from Teos; Myrlea from Colophon; Perinthus from Samos (600).
The Milesians also advanced into the Pontus at an early date. It was due to them that this sea, which, with its inhospitable shores peopled by wild barbarians, had been the terror of Grecian mariners, became known as “the hospitable sea” (Pontos Euxinos), with which few other regions could compare in importance for Grecian commerce. Miletus is said to have founded in all no less than ninety colonies on the coasts of the Hellespont and Pontus. In 630 Milesians built Sinope not far from the mouth of the Halys, which soon grew to be the most important emporium in this region, and founded in its turn a number of colonies, as Cotyora, Trapezus, and Cerasus. The Milesians, however, turned their attention especially to the northwest and north coasts of the Pontus, which were to become the principal granaries of Greece. After the middle of the seventh century a large number of Milesian colonies grew up here. The first was Istrus south of the mouth of the Danube, said to have been founded in 656; a few years later (644) Olbia, at the mouth of the Borysthenes near its junction with the Hypanis (Bug); then in the first half of the sixth century on the east coast of Thrace, Apollonia, Odessus, and Tomis; further on Tyras at the mouth of the river of like name (Dniester) and Theodosia on the south coast of the Crimea. The Hellenic settlements were especially frequent in the Cimmerian Bosporus, the highway uniting the Pontus with the sea of Mæotis. Nymphæum and the Milesian colony of Panticapæum, the later capital of the Bosporian kingdom, arose here on the western shore; opposite, on the Asiatic shore, was Phanagorea, founded from Teos. Finally, Tanais was founded at the mouth of the Don, the most northerly point ever occupied by the Greeks.
The Megarians had begun to establish themselves on the Propontis at about the same time with the Milesians. In 675 they founded Chalcedon at the entrance to the Thracian Bosporus, and seventeen years later, Byzantium, on the opposite European shore. Selymbria, neighbouring Byzantium on the west, and Astacus, at the most easterly point of the Propontis, not far from the site of the later Nicomedia, were Megarian colonies. The Megarians, however, penetrated into the Pontus itself, at a comparatively late date. Their first colony here was Heraclea, founded in association with Bœotian settlers in the year 550, in the land of the Mariandyni, about two hundred kilometres from the outlet of the Bosporus. From there Mesembria and Callatis were colonised on the east coast of Thrace, and Chersonesus, on the southern point of the Tauric peninsula, near the present Sebastopol.
All of these Grecian towns, however, remained with few exceptions isolated points in the midst of the original population of barbarians. An actual hellenising of the country as in Sicily and lower Italy was never accomplished. This was largely due to the configuration of the Pontine coast, which with the exception of the Crimea has no indentations, so that the Grecian colonies had no way to protect themselves against the attacks of the tribes from the interior. Besides, the winter climate of the regions north of the Pontus was very raw. The Greeks could not feel happy in a land where the vine and olive tree grew only in sheltered places, and only the bitterest necessity or the prospect of great commercial gain could cause them to leave their sunny home-land for such a country. Thus the Grecian cities on the Pontus never became very populous; there was not one among them to compare with Sybaris, Taras, Acragas, to say nothing of Syracuse. Condemned to a continual struggle for existence, the Greeks here had no leisure for the cultivation of higher interests. It is remarkable how poor the Pontine colonies have been in intellectual greatness. Their rôle in history has practically been confined to providing the mother-land with grain, salted fish, and other such raw products. Only once, when the rest of the nation had already fallen under foreign dominion, did they take an active part in great political events. The last battle for Grecian liberty was fought with their forces, but he who led the fight was a hellenised barbarian king.
Although the Hellenes had been able to expand on the Italian, Sicilian, and Pontine coasts with almost no hindrance, Grecian colonisation met an insurmountable obstacle in the old civilised lands on the southeastern shores of the Mediterranean, with their dense populations. In Syria the Hellenes did not attempt a settlement; they were not even able to drive the Phœnicians out of Cyprus. Indeed, when the Assyrian king Sargon conquered Syria at the end of the eighth century, the Greeks on Cyprus thought it advisable to recognise his supremacy, at least nominally, and this relation continued under his successors until Asshurbanapal. Later, after the fall of the Assyrian Empire, the island came under Egyptian rule. Sargon’s son Sennacherib (705-681) repulsed an attempt of the Greeks to settle on the Cilician plain. The warlike tribes of rough Cilicia and Lycia also succeeded in keeping the Greeks at a distance from their coasts, or at least prevented their further expansion. Phaselis, founded by the Rhodians on the western shore of the gulf of Pamphylia in 700, remained the last Grecian colony in the south of Asia Minor.
The rich valley of the Nile attracted Grecian pirates at an early period, the more so as the political divisions of the country in the eighth and first half of the seventh century rendered an effective resistance impossible. The superior military ability of these pirates finally caused Psamthek, the ruler of Saïs, to hire them as mercenaries. With their aid he got the upper hand over the other sectional princes and freed Egypt from the Assyrian yoke (about 660-645). From that time forward, Greeks formed the kernel of the Egyptian army, and although the Nile valley was now closed to piracy, it was, on the other hand, open to Greek commerce. The Milesians founded a colony on the Bolbitinic mouth of the Nile, below Saïs; somewhat later a number of Greek mercantile settlements grew up at Naucratis, not far from the Canopic mouth of the Nile, to which King Aahmes granted rights of corporation. The city soon grew to be the chief commercial emporium of Egypt and in the sixth century occupied, on a small scale, a position like that of the later Alexandria. In the course of time the Greeks would without doubt have become rulers of the country, but the Persian conquest retarded their development for fully a century and put a limit to the further expansion of Hellenism.