According to their shape the bacteria are divided into three chief groups, called respectively cocci, bacilli, and spirilla. The cocci are spherical bodies and may exist singly or in pairs, in fours, in clusters, or in chains. In this group we find the smallest bacteria known, many of them not over 1-150,000 of an inch in diameter. The bacilli are rod-like bodies, varying much in size in different species and in members of the same species. They are larger than the cocci, measuring in length from 1-25,000 of an inch to 1-4000, and in breadth from 1-125,000 to 1-16,000 of an inch. Many varieties are possessed of organs of locomotion called flagella.
The spirilla resemble the bacilli, except that they are twisted into corkscrew shapes, or have gently undulating outlines. Upon an average they are much longer than the bacilli, one species being very long, measuring about 1-600 of an inch. As seen in the natural state bacteria are found to be colorless, but it is by the application of various aniline dyes that they are usually studied. These minute plants increase by a simple method of division into two equal parts, or by a more complex process of forming a seed—the so-called spore—which later on develops into the adult form. Under favorable conditions they are able to multiply at an enormous rate; for instance, it has been calculated that a bacillus dividing once every hour would at the end of twenty-four hours have increased to seventeen millions; and if the division continued at the same rate we should find at the end of the third day an incalculable number of billions, whose weight would be nearly seven thousand five hundred tons!
But, fortunately for our welfare, nature by various means renders the possibility of such a happening entirely beyond the slightest chance of realization, her greatest barrier being the lack of an adequate food supply.
The distribution in nature of bacteria is wellnigh universal, occurring as they do in the air we breathe, the water and milk we drink, upon the exposed surfaces of man and animals, and in their intestinal tracts, and in the soil to a depth of about nine feet. But it has been noted that at very high altitudes and in glacier ice none exist, while in the Arctic regions and at sea far from land their numbers are very few.
The conditions governing their growth involve many complex problems, but a few of the chief factors concerned are moisture, air, food, temperature, and light. All bacteria must have moisture, else they die sooner or later, depending upon the hardness of the species, and none can multiply without it. A supply of air is by no means essential to all germs. To some it is absolutely necessary, and such germs are called aerobes. To others air is wholly detrimental, and they constitute the anaerobes, while to the majority of bacteria air supply is a matter of indifference, and in consequence they are grouped under the term facultative anaerobes.
The food supply of many consists of dead animal and vegetable materials, a few require living tissues, while a small number can exist wholly upon mineral salts, or even the nitrogen of the air. The lowest temperature at which some bacteria can multiply is the freezing-point of water, and the highest 170 degrees Fahrenheit. However, the average range of temperature suitable to the majority lies between 60 and 104 degrees Fahrenheit, 98 2-5 degrees Fahrenheit being the most suitable for the growth of disease-producing germs. Light, ordinarily diffused daylight, or its absence, is a matter of no moment to most germs, whereas direct sunlight is a destroyer of all bacteria.
The study of the life histories of these diminutive plants excites the wonder of those who make observations upon them. It is truly marvellous to know that these bacteria can accomplish in their short lives of possibly a few hours or days feats which would baffle the cleverest of chemists if given years of a lifetime to work upon. They give to the farmer the good quality of his crops, to the dairyman superior butter and cheese; they assist in large measure in freeing our rivers and lakes from harmful pollutions. Here it should be strongly emphasized that those bacteria which cause disease are only of a few species, all others contributing to our welfare in countless ways.
Quite as astonishing is the discovery that within the root-knobs of pease and beans live bacteria which by splitting up mineral salts containing nitrogen, and by absorbing nitrogen from the air, give it over to the plant so that it is enabled to grow luxuriantly, whereas, without their presence, the tiller of the soil might fertilize the ground in vain. It is quite possible that not alone pease and beans, but all grasses and plants and trees depend upon the presence of such germs for their very existence, which in turn supply man and animals with their means of existence. Hence we see that these nitrifying bacteria, as they are called, if swept out of existence, would be the cause of cessation of all life upon the globe. And arguing backward, one prominent authority states it as his belief that the first of all life on this earth were those lowly forms of plants which only required the nitrogen of air or salts to enable them to multiply.
Limiting observation now to the sphere of medicine, it will be readily perceived that the presence of bacterial life in a causative relation to disease is an object of paramount regard. The following paragraphs will briefly treat of the diseases associated with micro-organisms and the common modes of infection in each, the chain of events subsequent to an infection, and the possibilities of protection or cure by means of substances elaborated in the body of an individual or animal recently recovered from an infectious disease:
Anthrax.—A disease chiefly of cattle and sheep, occasionally of man, is caused by the Bacillus anthracis, discovered in 1849–50 by Pollender and Davaine. It enters the body through abrasions of the skin, by inhalation of the spores, or seeds, into the lungs, or by swallowing infected material.