I Received the letter, which you honoured me with, and the order for visiting the persons afflicted with the leprosy. I was sensible of the misfortune of being ordered upon that commission: I say misfortune; for such you will perhaps think it, when you have read this letter.
It is now about 25 or 30 years since a very particular disease shewed itself in many persons in this island Grande Terre. Its beginning is imperceptible: there appear but a few livid-red spots upon the skins of the white people, and of a yellowish red upon the blacks. These spots in the beginning are not accompanied with pain, or any other symptom; but nothing can take them away. The disease increases insensibly, and continues several years in shewing itself more and more. These spots increase, and extend indifferently over the skin of the whole body. Sometimes they are a little prominent, but flat. When the disease makes a progress, the upper part of the nose swells, the nostrils are enlarged, the nose becomes softened; tuberosities appear upon the cheek-bones; the eyebrows are inflated; the ears grow thick; the ends of the fingers, and even the feet and toes, swell; the nails become scaly; the joints of the feet and hands separate and mortify: ulcers of a deep and of a dry nature are found in the palms of the hands and soles of the feet, which grow well, and return again. In short, when the disease is in its last stage, the patient becomes frightful, and falls to pieces. All these symptoms come on by very slow degrees, one after another, and sometimes require many years to shew themselves: the patient is sensible of no sharp pain; but feels a kind of numbness in his hands and feet. These people perform their natural functions all the while, eating and drinking as usual: and even when the mortification has taken off the fingers and toes, the only ill consequence, that attends, is the loss of those parts, that drop off by the mortification; for the wound heals of itself, without any application: but when it comes to its last period, the poor sick persons are horribly deformed, and truly worthy of compassion.
This shocking disease is observed to have several other unhappy characters; as, 1st, that it is hereditary, and that some families are more apt to be seized with it than others: 2dly, that it is infectious, being communicated per coitum, and also caught by keeping company with those so diseased: 3dly, that it is incurable, or at least that no remedy has yet been found to cure it. They have in vain tried mercurials, sudorifics, and every other regimen used in venereal complaints, under a notion, that this leprosy was the consequence of some venereal taint: but, instead of being of service, these methods rather served to destroy the patients; for, far from lessening the disease, the antivenereal medicines unlocked the distemper, the most dreadful symptoms appeared, and all those so treated perished some years sooner than the others, who did not take these medicines.
A very just fear of being infected with this cruel distemper; the difficulty of examining infected persons before the disease came to its state; the length of time of its lying concealed, by the care of the patients to keep it secret; the uncertainty of the symptoms, which distinguish it in the beginning; produced an extraordinary dread in all the inhabitants of this island. They inspected one another, since virtue and merit had no shelter from this cruel scourge. They called this distemper the leprosy; and consequently presented several memoirs to the generals and intendants, laying before them all these facts above-mentioned; their just apprehensions; the public good; the trouble, that this distrust caused in this colony; the complaints and hatred, that these accusations occasioned among them; the laws made formerly against such leprous persons, and their expulsion from civil society. They required a general visitation of all persons suspected of this distemper, that such, as were found infected, might be removed into particular hospitals, or into some separate places.
These memorials were sent to court, which, giving due attention to these just representations, issued orders for the required visitations in the most convenient manner, for the good of the public and of the state.
In the mean time, the post of physician-botanist become vacant in the island of Cayenne. The minister was pleased to name me for it; and altho' this island was much more fertile in philosophical discoveries than all the others, he thought proper to change my destination, and sent me to this isle Guadaloupe; and did not forget the article of the leprosy in my instructions.
When I arrived at Martinico in 1727, Monsieur Blondel de Juvencourt, then intendant of the French isles, communicated to me both the orders of the court, and all the memoirs, that related to this affair. A tax was then laid upon the Negroes of the inhabitants of the Grande Terre, to raise a necessary fund for this visitation, thus made at the expence of the colony; and Mons. le Mercier Beausoleil was chosen treasurer of this fund.
Being arrived at Guadaloupe, the Count de Moyencourt, and Mons. Mesnier, ordinator and subdelegate to this intendance, communicated to me the order of the general and intendant. I began then to inform myself of the necessary instructions for acquiting myself of this dangerous commission, the disagreeable consequences of which I easily foresaw. I had so often heard of these leprous spots, that I judged it necessary to know, whether what was said was true: for I could not comprehend, that a disease, which has so dreadful an end, and the symptoms then so terrible, should continue ten or fifteen years without any other appearance than these simple spots; which, in themselves, had nothing very bad. I demanded an inquest to be made, in order to satisfy myself of this fact: several surgeons, as practitioners, and several honest inhabitants, as observers, were accordingly called together, who all proved the same fact in this inquest; which you, Sir, may, and must, have seen in the register of the subdelegation of this island. I am, most sincerely,
SIR,
Your most humble and obedient Servant,
Peyssonel.
August 10. 1748.