I was of an healthy constitution till the year 1730, when I was seized with a frequent inclination to make water, without any previous pain in the kidneys or ureters. This symptom continued till the year 1733, without giving me much uneasiness.

In June 1733, as I was riding from Edinburgh to my own house at Pencaitland, I was seized with a great difficulty and pain in making water, which went off when I got home.

In the month of July, having again got on horseback, I was seized with the same complaint, but more violent; for then some drops of blood came away. From this time, if I rode eight or ten miles, I passed some blood, but without pain.

In September I made a journey of 60 miles on horseback; but every two miles was obliged to dismount, and made some bloody water.

I continued much in the same way all the year 1734, as the preceding; only had one additional complaint, of a pain in the glans after making water, and likewise in the neck of the bladder. The only thing I did for it was, to drink plentifully of warm milk and water; and gave over riding, on account of the bloody urine.

In the month of August I was sounded by my nephew, Dr. Simson, professor of medicine in the university of St. Andrew's; but he found no stone, which he attributed to a wrong posture I was in, when he sounded me.

During the winter, if I walked more than usual, I was sure to have a return of the bloody urine and strangury.

In November 1735, I was sounded by Mr. Balderstone, surgeon, in Edinburgh, a gentleman very expert in that operation, and likewise by Dr. Drummond of Perthshire. They both distinctly felt a stone: and I myself took hold of the catheter, when it was in my bladder, and felt the stone as distinctly, as if it had been in my hand.

About Christmas I was seized with a pain along the left ureter, and violent vomitings; but, upon using a turpentine clyster and opiates, it went off.

During the year 1736, I continued much the same as the preceding year, always drinking great plenty of milk and water; which gave me great relief, as to the bloody urine.